{"id":"W4387733092","doi":"10.14309/01.ajg.0000954288.99982.31","title":"S1162 PRA023 Improved Bowel Urgency, Nocturnal Bowel Movement, Nocturnal Waking, and Abdominal Pain in a Phase 2 Trial of Patients With Moderately to Severely Active Ulcerative Colitis","year":2023,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Microscopic Colitis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Ulcerative colitis; Inflammatory bowel disease; Internal medicine; Abdominal pain; Placebo; Defecation; Gastroenterology; Clinical endpoint; Cohort; Irritable bowel syndrome; Pouchitis; Randomized controlled trial; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001186571,0.001027563,0.001810597,0.0003088847,0.0002929486,0.0008039951,0.000658576,0.001408009,0.007947515],"category_scores_gemma":[0.000942321,0.000388742,0.001267716,0.0003773901,0.0004165769,0.0004963704,0.0002936311,0.00241057,0.001130238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002796889,"about_ca_system_score_gemma":0.0006814993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004579533,"about_ca_topic_score_gemma":0.001274924,"domain_scores_codex":[0.9996008,0.0002288148,0.00003176929,0.00004905193,0.00003691204,0.00005253698],"domain_scores_gemma":[0.9994754,0.000111199,0.000130088,0.00003540142,0.00004576385,0.000202166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8934051,0.0152346,0.001806259,0.001575291,0.001712744,0.0001449299,0.00007833786,0.0006532648,0.02066603,0.0001388399,0.003409847,0.06117474],"study_design_scores_gemma":[0.8363532,0.153443,0.006696225,0.0000474327,0.0004099814,0.0001236533,0.00001830494,0.0006560527,0.001067975,0.00005918822,0.001101921,0.00002297557],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850032,0.005997651,0.0005304227,0.0009358175,0.0004678514,0.00176728,0.001356358,0.0002924594,0.003649134],"genre_scores_gemma":[0.9885319,0.002094724,0.001234229,0.001096148,0.0003356051,0.001366719,0.001989447,0.00002645517,0.003324632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007947515,"threshold_uncertainty_score":0.02658707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00971376804590277,"score_gpt":0.2862438301342266,"score_spread":0.2765300620883238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}