{"id":"W4387733114","doi":"10.14309/01.ajg.0000953884.54993.8f","title":"S1061 Efficacy and Safety of Etrasimod in Patients With and Without Concomitant Corticosteroid Treatment in the Phase 3 ELEVATE UC 52 and ELEVATE UC 12 Trials","year":2023,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pfizer (Canada); University of British Columbia","funders":"","keywords":"Medicine; Concomitant; Clinical endpoint; Placebo; Corticosteroid; Internal medicine; Ulcerative colitis; Prednisone; Gastroenterology; Randomized controlled trial; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003339401,0.000711045,0.002005874,0.0002641787,0.0003908622,0.0009879397,0.000364767,0.001188102,0.007350132],"category_scores_gemma":[0.002427095,0.0003235941,0.00201446,0.0004763858,0.0003857776,0.0007308083,0.0003555135,0.001980504,0.001046792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003362375,"about_ca_system_score_gemma":0.0007483442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002019366,"about_ca_topic_score_gemma":0.0008831287,"domain_scores_codex":[0.9983034,0.001049704,0.0002269907,0.0001648088,0.0001494617,0.0001056279],"domain_scores_gemma":[0.9983847,0.0005912161,0.0005483088,0.00009615646,0.0001365927,0.0002430223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.842021,0.004199812,0.01004575,0.004564252,0.004506472,0.0002690468,0.0001549353,0.0008170315,0.01407569,0.0003273206,0.00893134,0.1100873],"study_design_scores_gemma":[0.7393307,0.2007681,0.03776925,0.0007645411,0.00377051,0.0007699591,0.00009879306,0.001038264,0.002873237,0.0005912922,0.01215015,0.00007529282],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9229154,0.04606786,0.00110861,0.002443549,0.0005615483,0.004242763,0.007295122,0.0001462609,0.01521886],"genre_scores_gemma":[0.9771981,0.008059866,0.001389647,0.002534867,0.0005321429,0.003038079,0.004617356,0.0000261834,0.002603811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007350132,"threshold_uncertainty_score":0.0245887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0249835411761741,"score_gpt":0.3103217559892302,"score_spread":0.2853382148130561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}