{"id":"W4387733439","doi":"10.14309/01.ajg.0000953504.07738.1c","title":"S966 Persistence Among Patients with Ulcerative Colitis Previously Treated with an Anti-Tumor Necrosis Factor Inhibitor and Switching or Cycling to Another Biologic Agent","year":2023,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Group for Research in Decision Analysis","funders":"","keywords":"Medicine; Vedolizumab; Adalimumab; Infliximab; Ustekinumab; Golimumab; Internal medicine; Ulcerative colitis; Tumor necrosis factor alpha; Maintenance therapy; Gastroenterology; Oncology; Chemotherapy; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005035172,0.0001834799,0.0004006995,0.000901695,0.0004325263,0.000774278,0.0002674729,0.0004909096,0.005478433],"category_scores_gemma":[0.001721319,0.0001727181,0.0005469684,0.001676053,0.0002276316,0.0006214831,0.0004097395,0.0005373527,0.0007278819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003010557,"about_ca_system_score_gemma":0.0003730623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002135118,"about_ca_topic_score_gemma":0.001856951,"domain_scores_codex":[0.9994648,0.00008435992,0.0001319378,0.0001364282,0.0001040558,0.00007856268],"domain_scores_gemma":[0.9979565,0.0002392567,0.001244565,0.00007861487,0.00012941,0.0003515625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006189134,0.00007184994,0.9970242,0.00003814917,0.00005787726,0.0001020225,0.00005669506,0.00002626982,0.00008471273,0.00001759268,0.0002885196,0.001613075],"study_design_scores_gemma":[0.00009109513,0.0006778922,0.996603,0.00004947531,0.00007318506,0.0009217483,0.0002758203,0.0002523716,0.0000608317,0.00006108534,0.0009224056,0.00001096129],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971482,0.000419335,0.00003101797,0.00006675792,0.00001053928,0.00001622407,0.001721371,0.000003546647,0.0005829587],"genre_scores_gemma":[0.9973153,0.0002045521,0.00006478967,0.00006941432,0.00003187346,0.00002352267,0.001995381,0.000002614599,0.000292579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005478433,"threshold_uncertainty_score":0.01832724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01053213124894271,"score_gpt":0.2297022535552663,"score_spread":0.2191701223063236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}