{"id":"W4387733484","doi":"10.14309/01.ajg.0000953372.78170.a8","title":"S933 Durability of Symptomatic and Clinical Outcomes in Ozanimod-Treated Patients by Endpoints of Increasing Objectivity at True North Week 52: Interim Analysis of the True North Open-Label Extension Study","year":2023,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Discontinuation; Clinical endpoint; Interim analysis; Internal medicine; Clinical trial; Surgery; Physical therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006464163,0.0004854769,0.001328205,0.000213443,0.0002161459,0.0007468929,0.0003488617,0.0004326803,0.003013833],"category_scores_gemma":[0.002893345,0.0002390839,0.002074467,0.0002660991,0.0003858905,0.0006581875,0.0004803771,0.0011251,0.0003946864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002805713,"about_ca_system_score_gemma":0.0007321935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002076652,"about_ca_topic_score_gemma":0.0004349801,"domain_scores_codex":[0.9983907,0.0009086956,0.0001179314,0.0001573762,0.0002277295,0.0001976555],"domain_scores_gemma":[0.9969897,0.0009676069,0.001069434,0.00054852,0.0001854762,0.00023919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8172187,0.007384708,0.09894643,0.000469233,0.002987849,0.0001980567,0.0002004638,0.001805234,0.01049988,0.0002390884,0.00201125,0.05803912],"study_design_scores_gemma":[0.08283646,0.4323869,0.4563046,0.0001473371,0.004633197,0.0003777041,0.0002472406,0.005130184,0.01106192,0.0006992361,0.006075129,0.000100012],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957954,0.0005638471,0.00076768,0.00006749656,0.00003165142,0.0004178711,0.001135392,0.00002072278,0.001199894],"genre_scores_gemma":[0.9940037,0.000191327,0.0009803103,0.0001421969,0.00004607669,0.0008684703,0.002493439,0.000011783,0.001262643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006464163,"threshold_uncertainty_score":0.03418618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01793150482867931,"score_gpt":0.3043224346407279,"score_spread":0.2863909298120486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}