{"id":"W4387734986","doi":"10.1093/g3journal/jkad241","title":"Identification of pararosaniline as a modifier of RNA splicing in <i>Caenorhabditis elegans</i>","year":2023,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Tokyo Medical and Dental University; Harvard University; Canada Foundation for Innovation; U.S. Environmental Protection Agency; University of Minnesota; Office of Research and Development","keywords":"Biology; RNA splicing; RNA interference; Splicing factor; RNA; Alternative splicing; SR protein; Caenorhabditis elegans; Cell biology; Gene; Genetics; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001050161,0.0002925363,0.0002009446,0.0001496919,0.0001390818,0.0001501117,0.0002213993,0.0002689481,0.0006014712],"category_scores_gemma":[0.00008328468,0.0001398881,0.0002526365,0.00007182622,0.0001830453,0.0001197425,0.0001051718,0.0002850572,0.0001483855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002941722,"about_ca_system_score_gemma":0.0002203726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001501671,"about_ca_topic_score_gemma":0.002742722,"domain_scores_codex":[0.9998999,0.000008933306,0.000009065337,0.00003093482,0.0000335553,0.00001757373],"domain_scores_gemma":[0.9998957,0.00001436064,0.00004113194,0.0000106405,0.00001875472,0.0000194549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002281223,0.000005699752,0.00007776582,0.000007860205,0.000001099736,0.0000174605,0.000001670309,0.00001982611,0.9995459,0.00001191869,0.000005672367,0.0002824573],"study_design_scores_gemma":[0.000003602303,0.0001326927,0.001967223,0.000001256655,0.000004841585,0.0000473398,0.000003976024,0.0001996287,0.9972385,0.000007200063,0.0003919005,0.000001851303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954256,0.0004154198,0.002521541,0.00007264195,0.00001399112,0.00004530163,0.0003872402,0.00009354652,0.001024697],"genre_scores_gemma":[0.9905537,0.0004853356,0.005623027,0.00007911764,0.000007961777,0.00003754232,0.0005587468,0.00003780289,0.002616889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001501671,"threshold_uncertainty_score":0.002985895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01421199252261675,"score_gpt":0.28754823052324,"score_spread":0.2733362380006233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}