{"id":"W4387737168","doi":"10.1136/bjo-2023-323640","title":"<i>KCNV2</i>-associated retinopathy: genotype–phenotype correlations –<i>KCNV2</i>study group report 3","year":2023,"lang":"en","type":"article","venue":"British Journal of Ophthalmology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Janssen Pharmaceuticals; National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology; National Eye Institute; Moorfields Eye Charity; Moorfields Eye Hospital NHS Foundation Trust; Instituto de Salud Carlos III; Retina UK; Wellcome Trust; Active Biotech; Biogen; Ministry of Health, Labour and Welfare; Deutsche Forschungsgemeinschaft; Research to Prevent Blindness; Santen; National Institute for Health and Care Research; National Institutes of Health; Foundation Fighting Blindness; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research; Spark Therapeutics; Novartis","keywords":"Medicine; Ophthalmology; Electroretinography; Visual acuity; Retinal; Erg","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005839872,0.0006559482,0.0005032324,0.0004334666,0.0004636633,0.0007567039,0.000323829,0.0005775759,0.003650917],"category_scores_gemma":[0.001257681,0.0002655377,0.0005794101,0.00041221,0.0002683986,0.000277382,0.0003888664,0.000444823,0.000711043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002104865,"about_ca_system_score_gemma":0.0001936929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001214536,"about_ca_topic_score_gemma":0.0009730259,"domain_scores_codex":[0.999428,0.0001049976,0.0001032775,0.0002278511,0.00007166524,0.00006418782],"domain_scores_gemma":[0.9985833,0.0002798145,0.0006013038,0.0001481863,0.0001895912,0.0001977881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004198365,0.0002478291,0.9794653,0.0001023472,0.0004842838,0.001511171,0.0001662441,0.0001086017,0.006524234,0.00006164163,0.0008504281,0.006279655],"study_design_scores_gemma":[0.0005509056,0.001317408,0.9843722,0.00005606862,0.0005641996,0.009436813,0.0001944228,0.0003459127,0.001584519,0.0001067726,0.001439109,0.00003157779],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975866,0.0003795343,0.0003903341,0.00003869193,0.00001497914,0.00006316866,0.000645202,0.00001070868,0.0008707886],"genre_scores_gemma":[0.9974444,0.0001358458,0.0003305803,0.00006772998,0.000061127,0.00006097242,0.001468384,0.00001256859,0.0004184254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003650917,"threshold_uncertainty_score":0.01221347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01422125344359373,"score_gpt":0.2643689020181297,"score_spread":0.250147648574536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}