{"id":"W4387750109","doi":"10.14309/01.ajg.0000951636.24206.9b","title":"S499 The Efficacy and Safety of Vonoprazan, a Potassium-Competitive Acid Blocker, for the Treatment of Proton-Pump Inhibitor-Resistant Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis","year":2023,"lang":"en","type":"review","venue":"The American Journal of Gastroenterology","topic":"Gastroesophageal reflux and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; GERD; Internal medicine; Nerd; Proton-pump inhibitor; Adverse effect; Gastroenterology; Meta-analysis; Reflux; Pharmacology; Disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01108354,0.002160702,0.01616884,0.008117207,0.0005864967,0.003030839,0.00193345,0.002154554,0.005608781],"category_scores_gemma":[0.02336546,0.000956925,0.02804307,0.008339015,0.000709622,0.001792036,0.001088517,0.00117437,0.0004379481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0023606,"about_ca_system_score_gemma":0.004802976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005303932,"about_ca_topic_score_gemma":0.01264465,"domain_scores_codex":[0.992256,0.003026022,0.002873495,0.000620141,0.001006686,0.0002175047],"domain_scores_gemma":[0.9874833,0.008919661,0.002166099,0.0002750099,0.0009934022,0.0001625441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001281095,0.00002701405,0.002145562,0.6816352,0.3002235,0.0001191488,0.00008241274,0.0003671687,0.0002707575,0.0001194264,0.000695807,0.0130329],"study_design_scores_gemma":[0.0006079304,0.0002343078,0.003133989,0.06536873,0.9273875,0.0001203411,0.0000563104,0.0002158199,0.000158955,0.000173846,0.002515432,0.00002673123],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004236866,0.9932008,0.0004085157,0.0002085038,0.0001601361,0.0005446891,0.0008330815,0.00002293755,0.0003844941],"genre_scores_gemma":[0.1106431,0.8825242,0.001896547,0.001045409,0.0003306937,0.001854647,0.001176092,0.00002365858,0.0005056012],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01616884,"threshold_uncertainty_score":0.0586161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04734144029146096,"score_gpt":0.3517039708227357,"score_spread":0.3043625305312747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}