{"id":"W4387750822","doi":"10.14309/01.ajg.0000953240.16275.00","title":"S900 Response Trajectory by the Clinical Decision Support Tool Probability Groups in Vedolizumab-Treated Patients With Crohn’s Disease: A Pooled Analysis of GEMINI 2, VISIBLE 2, and VERSIFY","year":2023,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Vedolizumab; Inflammatory bowel disease; Abdominal pain; Crohn's disease; Internal medicine; Disease; Imputation (statistics); Physical therapy; Missing data; Gastroenterology; Machine learning","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02502336,0.00133782,0.005499658,0.001594292,0.0002279011,0.001877704,0.0006460149,0.001168035,0.00265618],"category_scores_gemma":[0.0284605,0.0006203245,0.02025891,0.001669176,0.0004062815,0.001256143,0.001054064,0.001038422,0.0002293505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006870804,"about_ca_system_score_gemma":0.0007484772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001117269,"about_ca_topic_score_gemma":0.001211924,"domain_scores_codex":[0.9800937,0.01427326,0.002378862,0.001521893,0.001303738,0.0004284656],"domain_scores_gemma":[0.9782251,0.01384473,0.005244091,0.001472519,0.0008583381,0.0003550897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"observational","study_design_scores_codex":[0.2807014,0.0004592787,0.08500226,0.01077924,0.5763433,0.0001124631,0.0002872818,0.003303119,0.001151928,0.0002563355,0.001787497,0.03981594],"study_design_scores_gemma":[0.04017954,0.02932115,0.2838222,0.002027196,0.6253777,0.000262466,0.0004426244,0.01019511,0.001337424,0.001310009,0.00548884,0.0002356419],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8717284,0.110395,0.007171893,0.0006875361,0.0004657581,0.0009869096,0.006594804,0.0001601489,0.001809488],"genre_scores_gemma":[0.9914684,0.003562024,0.001366776,0.0001980752,0.0001336627,0.0006144034,0.002267174,0.00002192109,0.0003675685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02502336,"threshold_uncertainty_score":0.1323377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007289760774106925,"score_gpt":0.2640908440041406,"score_spread":0.2568010832300336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}