{"id":"W4387751050","doi":"10.14309/01.ajg.0000953044.08925.8f","title":"S851 Efficacy and Safety of Guselkumab for Crohn’s Disease Through 3 Years: GALAXI-1 Long-Term Extension","year":2023,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Calgary","funders":"","keywords":"Medicine; Randomization; Randomized controlled trial; Ustekinumab; Adverse effect; Clinical endpoint; Intention-to-treat analysis; Internal medicine; Surgery; Psoriasis Area and Severity Index; Clinical trial; Disease; Psoriasis; Adalimumab; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001393344,0.0003840112,0.0009378694,0.000248388,0.000198787,0.0004478045,0.0003955007,0.0005917349,0.005057327],"category_scores_gemma":[0.0008011295,0.0001679933,0.0009440375,0.0002476446,0.0003170218,0.000503902,0.0003065831,0.00145568,0.0009248627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004916023,"about_ca_system_score_gemma":0.0006150432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000449118,"about_ca_topic_score_gemma":0.001471036,"domain_scores_codex":[0.9996953,0.0001159829,0.00002881649,0.0000441043,0.00005771606,0.00005815786],"domain_scores_gemma":[0.9995044,0.00008749264,0.0001859075,0.00003576944,0.00004634219,0.0001400364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.4700248,0.0143032,0.02339861,0.00365094,0.002579728,0.0003301089,0.0003976796,0.002230601,0.05692579,0.0005061503,0.00894928,0.4167032],"study_design_scores_gemma":[0.2591996,0.5331036,0.1755151,0.0004818281,0.003249539,0.0007243986,0.0001632932,0.002089713,0.01029869,0.0004186055,0.0146805,0.00007519413],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986673,0.007736158,0.0004092474,0.0004097258,0.00007931291,0.0004785581,0.001355823,0.0001235478,0.002734637],"genre_scores_gemma":[0.9921597,0.002256169,0.0006285129,0.0005947608,0.0001002937,0.0005160057,0.001902212,0.00001606337,0.001826314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005057327,"threshold_uncertainty_score":0.01691848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01054591630312456,"score_gpt":0.2689163045815983,"score_spread":0.2583703882784737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}