{"id":"W4387751123","doi":"10.14309/01.ajg.0000953252.60704.b9","title":"S903 Cumulative Response to Guselkumab Through Week 24 of Induction in Patients With Moderately to Severely Active Ulcerative Colitis: Results From the Phase 3 QUASAR Induction Study","year":2023,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; Western University","funders":"","keywords":"Medicine; Internal medicine; Population; Placebo; Surgery; Gastroenterology; Phases of clinical research; Clinical trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001650668,0.0005315279,0.001484371,0.0002340506,0.0002463557,0.0005009028,0.0003521476,0.0005522522,0.001894961],"category_scores_gemma":[0.0008170852,0.0002314147,0.001362595,0.000298007,0.0003221722,0.0004087614,0.0002531392,0.001593188,0.0006506686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003358659,"about_ca_system_score_gemma":0.0005541607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003613424,"about_ca_topic_score_gemma":0.0006747626,"domain_scores_codex":[0.9995512,0.000210961,0.0000372234,0.00005657107,0.00006905988,0.00007487719],"domain_scores_gemma":[0.9991811,0.0001447506,0.0002646396,0.00006853367,0.00006363531,0.0002773822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7418883,0.02373877,0.04200543,0.0007858648,0.002420363,0.0002280394,0.0002394954,0.001411007,0.04965255,0.00007432988,0.002541658,0.1350142],"study_design_scores_gemma":[0.1614613,0.6563595,0.1726206,0.00005482812,0.00116403,0.000341165,0.00006470887,0.001120039,0.004408213,0.00009627388,0.00226819,0.00004122949],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968778,0.00155018,0.0002290785,0.0001187512,0.0000221629,0.0002384278,0.0004383916,0.00004142025,0.0004838299],"genre_scores_gemma":[0.9970213,0.0006142325,0.0003089833,0.0002859728,0.00006494314,0.0002247486,0.0009037166,0.00001132061,0.0005648716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001894961,"threshold_uncertainty_score":0.008729637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02067607427645603,"score_gpt":0.2882475548398016,"score_spread":0.2675714805633456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}