{"id":"W4387751398","doi":"10.14309/01.ajg.0000953880.47700.a5","title":"S1060 Guselkumab Improves Health-Related Quality of Life in Patients With Moderately to Severely Active Ulcerative Colitis: Results From the QUASAR Phase 3 Induction Study","year":2023,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Barrie Urology Group; Western University; St. Paul's Hospital","funders":"","keywords":"Medicine; Ulcerative colitis; Internal medicine; Quality of life (healthcare); Population; Inflammatory bowel disease; Placebo; Clinical endpoint; Gastroenterology; Physical therapy; Randomized controlled trial; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001432855,0.0005060618,0.001458033,0.0001699251,0.0002144285,0.0004539471,0.000343748,0.0005224812,0.00270445],"category_scores_gemma":[0.0007396043,0.00021112,0.001106132,0.0002327217,0.0003826408,0.0002785632,0.0002305949,0.00108603,0.0005009689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002194548,"about_ca_system_score_gemma":0.0004636291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002815314,"about_ca_topic_score_gemma":0.0006014649,"domain_scores_codex":[0.999519,0.0002688226,0.00004548714,0.00004260178,0.00006653495,0.00005764614],"domain_scores_gemma":[0.999433,0.0001326298,0.0001562627,0.00004247674,0.00005100958,0.000184575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.770128,0.02112358,0.02351151,0.001075403,0.002799549,0.0001549621,0.0001927126,0.0008180739,0.04873379,0.00009538165,0.002451129,0.1289159],"study_design_scores_gemma":[0.3523659,0.4989885,0.141276,0.00007686695,0.001265657,0.0002634201,0.00006219256,0.0008600875,0.002785886,0.00009732298,0.001921406,0.00003682504],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958477,0.00250506,0.0002041073,0.0001407926,0.00003751756,0.0002957848,0.0003677764,0.0000325731,0.0005685823],"genre_scores_gemma":[0.9962269,0.00110448,0.0005375401,0.000392098,0.00009516701,0.0002931672,0.0007712808,0.000007462706,0.0005719232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00270445,"threshold_uncertainty_score":0.00904727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0182608713134918,"score_gpt":0.2907561201654132,"score_spread":0.2724952488519214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}