{"id":"W4387752321","doi":"10.14309/01.ajg.0000950388.31990.65","title":"S187 ADS024, a Bacillus velezensis Strain, for Prevention of Recurrence of Clostridioides difficile Infection: Results From a Randomized, Placebo-Controlled, Double-Blind, Phase 1b Study","year":2023,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Foothills Medical Centre","funders":"","keywords":"Medicine; Placebo; Clostridium difficile; Tolerability; Clinical endpoint; Internal medicine; Adverse effect; Gastroenterology; Dosing; Randomized controlled trial; Surgery; Antibiotics; Microbiology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001436977,0.00122271,0.001860622,0.0003700645,0.0003129638,0.0008283155,0.0006848397,0.00146628,0.005553313],"category_scores_gemma":[0.00092696,0.0004655503,0.001455095,0.0003730736,0.0007024207,0.0005398034,0.0002433018,0.001713768,0.0007327505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003990408,"about_ca_system_score_gemma":0.0007965538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005351523,"about_ca_topic_score_gemma":0.001078327,"domain_scores_codex":[0.9995342,0.000242965,0.00003984998,0.00007299174,0.00005156566,0.00005846957],"domain_scores_gemma":[0.9993663,0.0001597516,0.0001824754,0.00004172292,0.00005940754,0.0001902382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9131992,0.02442462,0.001488185,0.001659274,0.001639494,0.00009166377,0.00007519927,0.0003391417,0.01479841,0.00008268127,0.001505975,0.04069609],"study_design_scores_gemma":[0.7502923,0.240651,0.005125955,0.00006456176,0.0006992985,0.0000919093,0.0000376779,0.0002228045,0.001747484,0.00005376387,0.0009964904,0.00001673008],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989522,0.005550432,0.0003965081,0.000485177,0.0002265228,0.001555939,0.001097036,0.00009834331,0.00106804],"genre_scores_gemma":[0.9878615,0.004976983,0.0009946554,0.0008345878,0.0003917955,0.001372975,0.001406041,0.00002551027,0.002135828],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005553313,"threshold_uncertainty_score":0.01857764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05472662038818804,"score_gpt":0.3678718628284364,"score_spread":0.3131452424402484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}