{"id":"W4387774010","doi":"10.7554/elife.84515.sa0","title":"Editor's evaluation: The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Abscission; Midbody; Cell biology; Biology; ESCRT; Endosome; Protease; Mitosis; Cell division; Cytokinesis; Biochemistry; Intracellular; Cell; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006439795,0.001293755,0.00156152,0.001545627,0.001656152,0.004305042,0.003163235,0.005822143,0.05480225],"category_scores_gemma":[0.03078979,0.0006270303,0.000848059,0.0007882546,0.001316473,0.00229548,0.001541262,0.004228774,0.03212571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001685496,"about_ca_system_score_gemma":0.004007135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001122356,"about_ca_topic_score_gemma":0.003116873,"domain_scores_codex":[0.9950886,0.0005497347,0.0005719914,0.0005957801,0.002722458,0.0004714587],"domain_scores_gemma":[0.9632189,0.004463596,0.002034661,0.0009256097,0.02405397,0.005303251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005818305,0.00001643402,0.0001211162,0.0003130903,0.00001753568,0.0003177451,0.0000238612,0.00006096618,0.0003993456,0.0004359806,0.9776332,0.02060256],"study_design_scores_gemma":[0.00003149394,0.00002657775,0.0005003816,0.0001666684,0.00002015729,0.0005566895,0.00004888924,0.0002802066,0.0006072614,0.0004171002,0.9973245,0.00002010396],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.0004154718,0.003522228,0.0006904254,0.07437098,0.9153149,0.00006628958,0.0002098269,0.0002257351,0.005184175],"genre_scores_gemma":[0.007260901,0.007494453,0.001642793,0.04214855,0.8112692,0.00009313201,0.0004034692,0.000398838,0.1292886],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.05480225,"threshold_uncertainty_score":0.1833317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02923166587046628,"score_gpt":0.2829700916663357,"score_spread":0.2537384257958695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}