{"id":"W4387782619","doi":"10.3390/jdb11040039","title":"The New Nematicide Cyclobutrifluram Targets the Mitochondrial Succinate Dehydrogenase Complex in Caenorhabditis elegans","year":2023,"lang":"en","type":"article","venue":"Journal of Developmental Biology","topic":"Nematode management and characterization studies","field":"Agricultural and Biological Sciences","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Tarbiat Modares University; Université de Fribourg; University of Toronto; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Caenorhabditis elegans; Biology; Nematode; Gene; Mode of action; Transcriptome; Organism; Mitochondrion; Succinate dehydrogenase; Model organism; Cell biology; Genetics; Toxicology; Gene expression; Ecology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003394584,0.0001203448,0.0002165881,0.00003219182,0.0003697825,0.00006064802,0.0003890653,0.00004622433,0.0001211274],"category_scores_gemma":[0.00008823974,0.00003422239,0.00008328989,0.0005227699,0.00007822618,0.00007858803,0.0001457787,0.0001330809,0.00006296567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003642477,"about_ca_system_score_gemma":0.0000234651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004875319,"about_ca_topic_score_gemma":0.0008480413,"domain_scores_codex":[0.9988227,0.0001199249,0.0005118643,0.0001106371,0.0001485152,0.000286315],"domain_scores_gemma":[0.9992167,0.0003724369,0.0002748514,0.0000302783,0.0000511781,0.00005455548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001748299,0.00007467283,0.0371817,0.000009564887,0.000212985,0.0001006693,0.0009321097,0.00001006617,0.8434781,0.001253548,0.06806374,0.04850799],"study_design_scores_gemma":[0.0009644369,0.0002601706,0.5014019,0.00004110352,0.00002379596,0.0001205773,0.003745692,0.00004135953,0.0109317,0.004941189,0.4772491,0.0002789627],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820704,0.0001891435,0.000007412007,0.01679491,0.000501115,0.0001818584,0.00000878622,0.00001779235,0.0002285691],"genre_scores_gemma":[0.9977679,0.0006018458,0.0001463114,0.0004903543,0.0003682907,0.000008193868,0.00004227089,0.00000129845,0.0005735175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8325464,"threshold_uncertainty_score":0.2844105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02305211008158906,"score_gpt":0.2445389040507589,"score_spread":0.2214867939691699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}