{"id":"W4387787521","doi":"10.7554/elife.84515.sa1","title":"Decision letter: The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Abscission; Midbody; Cell biology; Biology; ESCRT; Endosome; Mitosis; Protease; Cytokinesis; Cell division; Intracellular; Biochemistry; Cell; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004863961,0.0006658473,0.001346673,0.001277074,0.002855102,0.005991688,0.001961733,0.01149414,0.1477253],"category_scores_gemma":[0.04329424,0.0005506476,0.0008946813,0.0008044013,0.001455241,0.003241981,0.001744479,0.00608576,0.1136477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00254575,"about_ca_system_score_gemma":0.005883419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002420586,"about_ca_topic_score_gemma":0.005755497,"domain_scores_codex":[0.9944773,0.0006456136,0.0005533624,0.0005080053,0.003049513,0.000766191],"domain_scores_gemma":[0.964456,0.00557741,0.001096299,0.001585217,0.02017675,0.007108312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006549931,0.00001638893,0.00006678925,0.00008152119,0.000005214722,0.0001624925,0.00001591275,0.00002332042,0.0002337044,0.001093356,0.9892508,0.008985094],"study_design_scores_gemma":[0.0000367964,0.00002465225,0.0004823752,0.00008397594,0.000006130586,0.0001350203,0.00004099332,0.0001816394,0.0004098535,0.001199016,0.9973828,0.00001667639],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"other","genre_scores_codex":[0.001334808,0.001476131,0.001702709,0.2666098,0.6594378,0.0005243048,0.002279625,0.001041758,0.065593],"genre_scores_gemma":[0.02007514,0.003764579,0.002859725,0.1275627,0.2279705,0.0004572311,0.002692364,0.001185354,0.6134323],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.1477253,"threshold_uncertainty_score":0.4941904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02239505582111946,"score_gpt":0.2615346183267624,"score_spread":0.2391395625056429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}