{"id":"W4387798740","doi":"10.1111/all.15928","title":"Antigens localized to B‐cell follicles are protected from proteases: Implications for allergy and allergen immunotherapy","year":2023,"lang":"en","type":"article","venue":"Allergy","topic":"Food Allergy and Anaphylaxis Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; McMaster University; Population Health Research Institute; McMaster University Medical Centre","funders":"Food Allergy Canada","keywords":"Proteases; Allergy; Immunology; Immunotherapy; Allergen; Antigen; Allergen immunotherapy; Anaphylaxis; Medicine; Oral immunotherapy; Biology; Immune system; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001782858,0.0002869444,0.0004423903,0.0003010476,0.0003224531,0.00005837519,0.000257924,0.0001865204,0.0002522533],"category_scores_gemma":[0.0001590686,0.0002581408,0.0001802022,0.0007528629,0.00008767612,0.00007363238,0.0001307053,0.0001797734,0.0001231144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000403978,"about_ca_system_score_gemma":0.0001493947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007213528,"about_ca_topic_score_gemma":0.001027323,"domain_scores_codex":[0.9979591,0.00007070182,0.0003840189,0.0006736073,0.0002785592,0.0006339661],"domain_scores_gemma":[0.9984627,0.000164525,0.00009407649,0.000624891,0.0002643743,0.0003893769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006168934,0.001562634,0.001715018,0.0003420969,0.00464152,0.0001094364,0.002618604,0.0004572879,0.7422804,0.002351402,0.1692041,0.06854861],"study_design_scores_gemma":[0.005063094,0.001109592,0.09002215,0.0001564278,0.000007341625,0.000008629993,0.0005423595,0.001053936,0.01047495,0.002047457,0.889037,0.0004770351],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9515811,0.003298853,0.003336844,0.03321236,0.0001718925,0.005907336,0.0004631159,0.0007414019,0.001287069],"genre_scores_gemma":[0.9619389,0.005705295,0.009057618,0.003170872,0.0006788091,0.006184135,0.001317146,0.0002937339,0.01165356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7318054,"threshold_uncertainty_score":0.9999871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03570905659882351,"score_gpt":0.3175055363904081,"score_spread":0.2817964797915846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}