{"id":"W4387810553","doi":"10.1016/j.annonc.2023.09.2572","title":"1623P Pelareorep (pela) + atezolizumab (atezo) and chemotherapy in first-line (1L) advanced or metastatic pancreatic ductal adenocarcinoma (PDAC) patients: Results from the GOBLET study","year":2023,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"","keywords":"Medicine; Internal medicine; Oncology; Progressive disease; Atezolizumab; Gemcitabine; Chemotherapy; Cancer; Gastroenterology; Immunotherapy; Nivolumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003495627,0.0002073337,0.0004018638,0.00008323064,0.00008572593,0.00001514762,0.0002457104,0.00009137011,0.0000351309],"category_scores_gemma":[0.00046722,0.0001410593,0.00006784633,0.0003072985,0.0001589145,0.00001120556,0.0001892628,0.0001239492,0.00001353952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003133457,"about_ca_system_score_gemma":0.0001610068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001851838,"about_ca_topic_score_gemma":0.008116707,"domain_scores_codex":[0.9981821,0.0002391511,0.0004496124,0.0005046774,0.0002109523,0.0004135353],"domain_scores_gemma":[0.998871,0.0002647479,0.0001827862,0.0004475093,0.0001384627,0.00009551988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.05237934,0.006623803,0.7665271,0.0001097533,0.002791806,0.0009436382,0.005953811,0.0002984501,0.004465276,0.00002392315,0.01954925,0.1403338],"study_design_scores_gemma":[0.02890124,0.02650024,0.9208195,0.00006033657,0.00009548535,0.00001722365,0.001825161,0.000100924,0.005631827,0.0005750678,0.01514102,0.0003319711],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945635,0.001108978,0.000002915492,0.002709877,0.00007135332,0.0009136433,0.0004438749,0.00001189872,0.0001739449],"genre_scores_gemma":[0.9937494,0.004703261,0.00008187897,0.0003894049,0.00006287853,0.0001517461,0.000616517,0.0000262609,0.0002185938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1542924,"threshold_uncertainty_score":0.5752229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06656061876900553,"score_gpt":0.3792253383067788,"score_spread":0.3126647195377733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}