{"id":"W4387811078","doi":"10.1016/j.annonc.2023.09.2223","title":"1089P Adjuvant nivolumab (NIVO) vs ipilimumab (IPI) in resected stage III/IV melanoma: 7-y results from CheckMate 238","year":2023,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Ono Pharmaceutical; Bristol-Myers Squibb","keywords":"Medicine; Ipilimumab; Nivolumab; Internal medicine; Oncology; Adjuvant; Melanoma; Stage (stratigraphy); Adjuvant therapy; Immunotherapy; Cancer; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007562119,0.0004831577,0.001039665,0.0002888707,0.0002253214,0.0006676409,0.0003907558,0.0006210601,0.001708616],"category_scores_gemma":[0.0006179375,0.0001805249,0.00148609,0.000207788,0.0003328187,0.0005230471,0.00021998,0.001148997,0.0005276788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006446151,"about_ca_system_score_gemma":0.0004966661,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002241326,"about_ca_topic_score_gemma":0.003184083,"domain_scores_codex":[0.9997904,0.00006861909,0.00000995064,0.00004794631,0.00002894861,0.0000542786],"domain_scores_gemma":[0.9995166,0.0001593639,0.00006385574,0.00005815157,0.00003544991,0.0001664861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7059501,0.01411054,0.09498625,0.0004348707,0.002979247,0.0005855431,0.0002199717,0.002159268,0.02007026,0.0001769062,0.005079569,0.1532474],"study_design_scores_gemma":[0.1115776,0.3716362,0.4849541,0.0001791581,0.007657289,0.001065299,0.0003400187,0.004345193,0.009048416,0.0004523671,0.008657686,0.00008660489],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959975,0.001854405,0.00007814662,0.0002019862,0.00008564452,0.00006570903,0.0007051419,0.0000215485,0.0009899321],"genre_scores_gemma":[0.9938284,0.001287772,0.0002393045,0.0003632396,0.0001303013,0.00006640208,0.002324502,0.00002021581,0.001739885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002241326,"threshold_uncertainty_score":0.005715907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0882871583234907,"score_gpt":0.3801278779248938,"score_spread":0.2918407196014031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}