{"id":"W4387811452","doi":"10.1016/j.annonc.2023.09.1928","title":"749P Patient-reported outcomes (PROs) in patients (pts) with mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) primary advanced or recurrent endometrial cancer (pA/rEC) in the ENGOT-EN6-NSGO/GOG3031/RUBY trial","year":2023,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"PharmaMar; Eisai; Sumitomo Dainippon Pharma Oncology; Seagen; Clovis Oncology; Incyte; Novocure; Sanofi; Exelixis; Regeneron Pharmaceuticals; Mersana Therapeutics; AstraZeneca; Pfizer; Amgen","keywords":"Medicine; Endometrial cancer; Internal medicine; Quality of life (healthcare); Population; Placebo; Oncology; Urology; Gastroenterology; Cancer; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009312286,0.0004436251,0.0008226,0.0001531588,0.0001415036,0.0007072853,0.0002141702,0.0005604583,0.00321555],"category_scores_gemma":[0.001144037,0.0001443098,0.00158892,0.0003236083,0.0002489373,0.000540119,0.0002892596,0.001384928,0.0004599914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000325295,"about_ca_system_score_gemma":0.0002701328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003799277,"about_ca_topic_score_gemma":0.0009118427,"domain_scores_codex":[0.9996081,0.0002264288,0.00002035024,0.00005306357,0.00002903077,0.00006302885],"domain_scores_gemma":[0.9996011,0.0001379472,0.0001175832,0.00002744122,0.00001944787,0.00009657026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.752134,0.001020622,0.07094181,0.002719716,0.01221931,0.0006203312,0.0001204541,0.004914694,0.007637222,0.001857336,0.01105044,0.134764],"study_design_scores_gemma":[0.3065543,0.1143375,0.4884276,0.0009443916,0.03599979,0.001619655,0.000450463,0.006986406,0.003906672,0.008557036,0.03203119,0.0001850791],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9725325,0.01459452,0.000516461,0.00148549,0.0004099679,0.0001417942,0.00350429,0.00006565225,0.006749421],"genre_scores_gemma":[0.9925975,0.002387033,0.0001797444,0.000716652,0.0001864305,0.0001250111,0.002223553,0.00001057077,0.001573413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00321555,"threshold_uncertainty_score":0.01075709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08075554179485443,"score_gpt":0.3753753084850433,"score_spread":0.2946197666901889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}