{"id":"W4387827282","doi":"10.1016/j.vetpar.2023.110055","title":"Inhibitory effects on bovine babesial infection by iron chelator, 1-(N-acetyl-6-aminohexyl)− 3-hydroxy-2-methylpyridin-4-one (CM1), and antimalarial drugs","year":2023,"lang":"en","type":"article","venue":"Veterinary Parasitology","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Research Council of Thailand; Chiang Mai University; Canadian Mennonite University","keywords":"Diminazene; Biology; Babesia; Babesiosis; Chloroquine; Pharmacology; Babesia bovis; IC50; Drug; Babesia bigemina; Microbiology; Malaria; Plasmodium falciparum; Plasmodium vivax; Virology; Primaquine; In vitro; Immunology; Trypanosomiasis; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003320368,0.0005507724,0.0007655332,0.0004571376,0.0004495357,0.00003648325,0.0001862363,0.000854153,0.000231688],"category_scores_gemma":[0.0002133362,0.0005904653,0.0001779294,0.0004290724,0.0004948017,0.0002198141,0.0002743556,0.0006454476,0.002094308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001265235,"about_ca_system_score_gemma":0.00006905675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002676329,"about_ca_topic_score_gemma":0.000008998724,"domain_scores_codex":[0.9966998,0.0008588279,0.0004729055,0.0009674257,0.0001011003,0.0008999043],"domain_scores_gemma":[0.9984741,0.000690388,0.0002246252,0.0004466388,0.00005033932,0.0001139532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001601998,0.0004641643,0.05142622,0.0001781634,0.000321876,0.0001523436,0.0001775907,0.000008327632,0.9224184,0.0001463365,0.01879231,0.00431225],"study_design_scores_gemma":[0.009440902,0.02155963,0.6712617,0.0001611333,0.0004196116,0.001425507,0.0000480904,0.00005466192,0.2289635,0.000154813,0.06504316,0.001467278],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917326,0.001015598,0.00003349303,0.0003534243,0.004686278,0.0006251489,0.00009013224,0.0008084786,0.0006548435],"genre_scores_gemma":[0.9976178,0.0003978425,0.00001561296,0.0002920655,0.0004727073,0.0001611562,0.0004341918,0.000083696,0.000524912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6934549,"threshold_uncertainty_score":0.9996547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01200769578867071,"score_gpt":0.2733803500504573,"score_spread":0.2613726542617866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}