{"id":"W4387854803","doi":"10.1093/ecco-jcc/jjad180","title":"Analysis of Clinical Trial Screen Failures in Inflammatory Bowel Diseases [IBD]: Real World Results from the International Organization for the study of IBD","year":2023,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Randomized controlled trial; Inflammatory bowel disease; Internal medicine; Crohn's disease; Placebo; Inflammatory Bowel Diseases; Disease; Clinical trial; Retrospective cohort study; Physical therapy; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.4015034,0.001841469,0.004216833,0.007221768,0.001264539,0.004219355,0.002237228,0.002600949,0.003303474],"category_scores_gemma":[0.5942088,0.001221157,0.009594139,0.01017997,0.002815082,0.002616709,0.003861674,0.002194377,0.0006031771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003003138,"about_ca_system_score_gemma":0.003753596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001359991,"about_ca_topic_score_gemma":0.001717934,"domain_scores_codex":[0.3773308,0.4959787,0.07436904,0.009845212,0.04006092,0.002415437],"domain_scores_gemma":[0.1126644,0.6293492,0.2033213,0.03468047,0.01743878,0.002545751],"domain_codex":"methods","domain_gemma":"methods","domain_candidate":"methods","domain_consensus":"methods","study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.04409498,0.0008275551,0.757587,0.03056927,0.05649986,0.0003326234,0.004063779,0.002800334,0.0006481931,0.00161996,0.00731684,0.09363969],"study_design_scores_gemma":[0.006637518,0.009237948,0.9236637,0.006453772,0.02973333,0.001102905,0.001283534,0.00453838,0.001308387,0.001284896,0.01449091,0.0002648232],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7815551,0.1395375,0.03473796,0.006620988,0.0005751509,0.01055648,0.01676303,0.0004769308,0.00917678],"genre_scores_gemma":[0.981055,0.003390427,0.005554448,0.001024079,0.0001773732,0.004960143,0.003420156,0.0001175805,0.0003008353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5984967,"threshold_uncertainty_score":0.738053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02301058590804062,"score_gpt":0.3190040880732559,"score_spread":0.2959935021652153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}