{"id":"W4387869089","doi":"10.7554/elife.91461.1","title":"Disordered regions and folded modules in CAF-1 promote histone deposition in S. pombe","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"French Infrastructure for Integrated Structural Biology; Institut National Du Cancer; Agence Nationale de la Recherche; Infrastructures en Biologie Santé et Agronomie","keywords":"Histone; Cell biology; DNA replication; Nucleosome; Chemistry; Biology; DNA; Genetics; Biophysics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006135728,0.0002029256,0.0001448907,0.00008768233,0.0001545647,0.0002056336,0.000156751,0.0001761418,0.0007782725],"category_scores_gemma":[0.0000923429,0.000137963,0.0001710255,0.00008674365,0.0001671437,0.0001198701,0.0001618343,0.0002945491,0.0002403042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003316224,"about_ca_system_score_gemma":0.0001443562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001809797,"about_ca_topic_score_gemma":0.001920739,"domain_scores_codex":[0.9999751,0.000003088464,0.000001348268,0.000007766417,0.000006009693,0.000006806511],"domain_scores_gemma":[0.999956,0.000008865975,0.00001193649,0.000004463172,0.000003481071,0.00001530379],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001513686,0.00002476689,0.0008733791,0.00002742595,0.000008719804,0.0001090119,0.00002892264,0.0009219628,0.9969226,0.0001915993,0.00005379203,0.0006865296],"study_design_scores_gemma":[0.00004002327,0.0001239702,0.01168913,0.00001200311,0.00001631623,0.0001872664,0.00008850056,0.01285904,0.9723002,0.0003422669,0.002327819,0.00001348686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984683,0.0001502082,0.0009934887,0.0000339678,0.000003318725,0.00000160249,0.0001112317,0.00003954944,0.0001983108],"genre_scores_gemma":[0.9979733,0.0000853667,0.001114406,0.0000175374,0.000001410936,0.000002311004,0.0002102069,0.00001795174,0.0005776202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001809797,"threshold_uncertainty_score":0.003598511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01199688389455998,"score_gpt":0.2538837412190851,"score_spread":0.2418868573245251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}