{"id":"W4387875381","doi":"10.1038/s41598-023-45102-6","title":"GWAS for the composite traits of hematuria and albuminuria","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network; University of Toronto; SickKids Foundation; Public Health Ontario; Université de Montréal; Montreal Heart Institute","funders":"Common Fund; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Cancer Institute; NIH Office of the Director; National Human Genome Research Institute; Institut de Valorisation des Données; National Institute on Drug Abuse; National Institute of Mental Health; National Heart, Lung, and Blood Institute; Fonds de Recherche du Québec - Santé; National Institutes of Health; Canadian Institutes of Health Research; Regeneron Pharmaceuticals; Alliance de recherche numérique du Canada; Alport Syndrome Foundation","keywords":"Genome-wide association study; Albuminuria; Medicine; Locus (genetics); Linkage disequilibrium; Genetics; Biology; Internal medicine; Haplotype; Kidney disease; Single-nucleotide polymorphism; Allele; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005617003,0.0004769133,0.0007140331,0.000646223,0.0005444104,0.0007142659,0.0002938725,0.0006074923,0.005608195],"category_scores_gemma":[0.001916392,0.000317862,0.0008531628,0.00162466,0.0002422386,0.0001662508,0.0006704608,0.0005947032,0.0003495924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004124705,"about_ca_system_score_gemma":0.0003669303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01575723,"about_ca_topic_score_gemma":0.0170212,"domain_scores_codex":[0.9991537,0.0001905127,0.00007150428,0.0002914072,0.0001688225,0.0001240456],"domain_scores_gemma":[0.9992275,0.0001690936,0.0002523896,0.0001385375,0.00008513036,0.0001272829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002891133,0.00006329692,0.9545582,0.0003361129,0.002963822,0.002209507,0.0003691654,0.0005396407,0.01407342,0.001111762,0.007815821,0.01306815],"study_design_scores_gemma":[0.00009541559,0.00008965183,0.9948648,0.0000358926,0.0003674712,0.0008053041,0.0000336894,0.000360873,0.0003022396,0.0002264572,0.002806618,0.00001178146],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818138,0.002838321,0.002234271,0.0003787231,0.0001238686,0.00008042269,0.009890334,0.0001457125,0.002494667],"genre_scores_gemma":[0.993292,0.0004653638,0.001195206,0.0001423419,0.00005794068,0.0000521627,0.002771905,0.00002299897,0.0020002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01575723,"threshold_uncertainty_score":0.031331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01917529787463657,"score_gpt":0.2853147999218614,"score_spread":0.2661395020472248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}