{"id":"W4387877261","doi":"10.1097/01.tp.0000993740.98367.bd","title":"105.6: Engineering a vascularized bioartificial pancreas for stem cell derived islet maturation","year":2023,"lang":"en","type":"article","venue":"Transplantation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Université Laval; University of British Columbia; McGill University","funders":"","keywords":"Transplantation; Biomedical engineering; Stem cell; Induced pluripotent stem cell; Mesenchymal stem cell; Progenitor cell; Cell biology; Pancreatic islets; Islet; Cell encapsulation; PDX1; Tissue engineering; Insulin; Chemistry; Materials science; Biology; Medicine; Internal medicine; Embryonic stem cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002154018,0.0003196939,0.0001363859,0.0002708474,0.0001011108,0.0004968326,0.0002272515,0.0004829604,0.001345054],"category_scores_gemma":[0.0001199447,0.0001181686,0.0002961191,0.0001536935,0.0001570476,0.0002037139,0.0001746099,0.0002640547,0.0005126254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001789227,"about_ca_system_score_gemma":0.0001433717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001280571,"about_ca_topic_score_gemma":0.0002039119,"domain_scores_codex":[0.999911,0.00001009592,0.000008941844,0.00001457905,0.00004156035,0.00001386264],"domain_scores_gemma":[0.999935,0.000009280765,0.00002179962,0.000006015577,0.000009618604,0.00001823912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002837892,0.00001581531,0.0001366674,0.00006199668,0.00000375777,0.0000735062,0.00001542076,0.0002671404,0.9957758,0.0002074921,0.0000841021,0.003329964],"study_design_scores_gemma":[0.00001044122,0.0001774713,0.001246394,0.00001132606,0.00001720776,0.000333573,0.000007407793,0.001519165,0.990876,0.0000720338,0.005723565,0.000005523083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9234626,0.002397447,0.06316932,0.0001595462,0.000166589,0.0001235788,0.000720024,0.0007932367,0.009007617],"genre_scores_gemma":[0.9319192,0.001580151,0.05816049,0.00008893511,0.00002802524,0.0001306242,0.001249618,0.0001127603,0.006730283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001345054,"threshold_uncertainty_score":0.004499674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01924783485007139,"score_gpt":0.2365063076040589,"score_spread":0.2172584727539875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}