{"id":"W4387880525","doi":"10.3390/cells12202508","title":"Suspension-Induced Stem Cell Transition: A Non-Transgenic Method to Generate Adult Stem Cells from Mouse and Human Somatic Cells","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; Institute of Infection and Immunity; Hospital for Sick Children; University of Ottawa","funders":"Academia Sinica; Ottawa Hospital Research Institute; Canadian Institutes of Health Research; University of Ottawa","keywords":"Stem cell; Cell biology; Somatic cell; Biology; Extracellular matrix; Fibroblast; Adult stem cell; Cell culture; Mesenchymal stem cell; Genetically modified mouse; Cellular differentiation; Anoikis; Stromal cell; Cell type; Transgene; Cell; Molecular biology; Genetics; Gene; Cancer research; Programmed cell death","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005054306,0.0004159957,0.0003009395,0.0008057533,0.0003000094,0.0004350266,0.0005220125,0.0004644339,0.001834178],"category_scores_gemma":[0.0002241211,0.0001991294,0.0005712571,0.0003687146,0.0003753465,0.0002910724,0.0004774792,0.000993414,0.001544672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001775529,"about_ca_system_score_gemma":0.000358707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001965984,"about_ca_topic_score_gemma":0.0004448538,"domain_scores_codex":[0.9996561,0.00005427084,0.0000367133,0.00006938256,0.0001602595,0.00002324996],"domain_scores_gemma":[0.9998086,0.00005100861,0.00003801857,0.00004188597,0.00003000026,0.00003047854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003764819,0.00004818492,0.0001606219,0.00007943252,0.000007510582,0.00008564672,0.00003006655,0.00006263832,0.9891263,0.0004960035,0.0003355193,0.009530348],"study_design_scores_gemma":[0.00002723945,0.000531576,0.001538641,0.00001653442,0.00003940658,0.001431511,0.00002527626,0.00121751,0.9695374,0.000284252,0.02533366,0.00001689711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2609061,0.008565152,0.7080381,0.0008635002,0.0008822219,0.001730088,0.00269742,0.00391256,0.01240489],"genre_scores_gemma":[0.6363369,0.008302626,0.323655,0.0007418549,0.0002651787,0.001564734,0.006613307,0.0004651529,0.02205517],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001834178,"threshold_uncertainty_score":0.006135941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02121716525803834,"score_gpt":0.2779384871337415,"score_spread":0.2567213218757031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}