{"id":"W4387880525","doi":"10.3390/cells12202508","title":"Suspension-Induced Stem Cell Transition: A Non-Transgenic Method to Generate Adult Stem Cells from Mouse and Human Somatic Cells","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; Institute of Infection and Immunity; Hospital for Sick Children; University of Ottawa","funders":"Academia Sinica; Ottawa Hospital Research Institute; Canadian Institutes of Health Research; University of Ottawa","keywords":"Stem cell; Cell biology; Somatic cell; Biology; Extracellular matrix; Fibroblast; Adult stem cell; Cell culture; Mesenchymal stem cell; Genetically modified mouse; Cellular differentiation; Anoikis; Stromal cell; Cell type; Transgene; Cell; Molecular biology; Genetics; Gene; Cancer research; Programmed cell death","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005263325,0.0004816687,0.0005064643,0.0002107558,0.000276801,0.0001372011,0.0005020492,0.0003869963,0.00006686838],"category_scores_gemma":[0.000001681615,0.0004849117,0.0002216346,0.0004204294,0.00005115606,0.00001407859,0.00024498,0.0002730977,0.0008804302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004308732,"about_ca_system_score_gemma":0.0001034411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001745083,"about_ca_topic_score_gemma":0.00008184189,"domain_scores_codex":[0.9965118,0.0004118488,0.000568164,0.001182693,0.0004826285,0.0008428539],"domain_scores_gemma":[0.9981688,0.00007695552,0.0001141542,0.0009079585,0.00019364,0.0005385219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007164738,0.00009743054,0.000009600908,0.0001933633,0.0000796449,0.00005620771,0.000641253,0.0009349101,0.9923267,0.000001967237,0.004767849,0.0008194574],"study_design_scores_gemma":[0.001269303,0.0003754418,0.00004284184,0.00005224142,0.00006391122,0.000003347923,0.0006337053,0.001426647,0.9942309,0.00001464438,0.001329853,0.0005572083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934921,0.00012227,0.004214235,0.000196245,0.0002916306,0.001073337,0.0002459956,0.000081674,0.000282557],"genre_scores_gemma":[0.9869227,0.0002477499,0.002261552,0.0004064354,0.000278591,0.00008850704,0.0002072671,0.0001320206,0.00945512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009172563,"threshold_uncertainty_score":0.9998975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02121716525803834,"score_gpt":0.2779384871337415,"score_spread":0.2567213218757031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}