{"id":"W4387902661","doi":"10.3390/curroncol30110681","title":"The Gut Microbiome from a Biomarker to a Novel Therapeutic Strategy for Immunotherapy Response in Patients with Lung Cancer","year":2023,"lang":"en","type":"review","venue":"Current Oncology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Seerave Foundation","keywords":"Medicine; Microbiome; Biomarker; Immunotherapy; Dysbiosis; Lung cancer; Immune system; Cancer; Immunology; Clinical trial; Adjuvant; Gut flora; Oncology; Bioinformatics; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006818784,0.0007593195,0.001308541,0.001294338,0.0001783087,0.000860107,0.0004860418,0.00113151,0.001711832],"category_scores_gemma":[0.001274234,0.0001668018,0.0006196868,0.0009699474,0.0003377258,0.0008662302,0.000631908,0.001647691,0.0007610313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005071976,"about_ca_system_score_gemma":0.0008952915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007004284,"about_ca_topic_score_gemma":0.001484809,"domain_scores_codex":[0.9997891,0.0000657541,0.00003109128,0.00003532106,0.00006063714,0.00001814351],"domain_scores_gemma":[0.9994925,0.0003044469,0.00005542212,0.00000848015,0.0001059454,0.00003317464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001164027,0.00004838531,0.0005272322,0.01384075,0.0002023226,0.0001353701,0.00004742322,0.0001773467,0.0009212113,0.002116644,0.01963193,0.962235],"study_design_scores_gemma":[0.00004144806,0.0002775087,0.004448522,0.01331966,0.0006114552,0.001803298,0.0001514829,0.0002277482,0.0006096644,0.003085957,0.9753799,0.00004320938],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000948067,0.9989405,0.00006798915,0.0004623615,0.000184987,0.000002483095,0.00001090735,0.000002649276,0.0002333251],"genre_scores_gemma":[0.0008752658,0.9981596,0.000141148,0.000325942,0.0002422498,0.000005446608,0.00001955963,0.000001038293,0.0002297049],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001711832,"threshold_uncertainty_score":0.005726695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1572704803849971,"score_gpt":0.474397762272766,"score_spread":0.3171272818877689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}