{"id":"W4387934102","doi":"10.1016/j.jcjd.2023.10.336","title":"NOX5 LINKS OXIDATIVE STRESS AND ENDOPLASMIC RETICULUM STRESS TO ENABLE VASCULAR SMOOTH MUSCLE CELL PHENOTYPIC SWITCHING IN HYPERTENSION","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Endoplasmic reticulum; Medicine; Oxidative stress; Phenotype; Cell biology; Cell; Internal medicine; Genetics; Gene; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003257639,0.0001721055,0.0001709347,0.0001260536,0.0002905348,0.0005865798,0.0002885792,0.000367015,0.001533567],"category_scores_gemma":[0.000188332,0.0001331908,0.0002858491,0.00008260769,0.000215057,0.0003316126,0.0003998959,0.0005398286,0.0001910005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005416953,"about_ca_system_score_gemma":0.0003470325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00146625,"about_ca_topic_score_gemma":0.00230902,"domain_scores_codex":[0.9998153,0.00003247008,0.00001199647,0.00002556873,0.00003195305,0.00008271229],"domain_scores_gemma":[0.9999073,0.000005828188,0.00002182077,0.00001017893,0.00001618592,0.00003871099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007695802,0.0001229172,0.003982843,0.0001125315,0.00003692141,0.0006094286,0.0001270068,0.000227398,0.9792832,0.005166979,0.00072711,0.008834227],"study_design_scores_gemma":[0.00009399234,0.0008751634,0.1196171,0.00005988315,0.0001025955,0.00146104,0.0007990305,0.003875245,0.8499223,0.004102996,0.01905429,0.00003628711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985495,0.004359857,0.004401456,0.001124379,0.000255437,0.00002274704,0.0001706782,0.00008895496,0.004081612],"genre_scores_gemma":[0.9966291,0.0006816213,0.0004871319,0.0001035141,0.00001557744,0.000005307358,0.00007130435,0.000006955252,0.001999581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001533567,"threshold_uncertainty_score":0.005130291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008834896201282133,"score_gpt":0.2042982173445393,"score_spread":0.1954633211432572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}