{"id":"W4387934183","doi":"10.1093/jcag/gwad027","title":"An Update on Anti-TNF Biosimilar Switching—Real-World Clinical Effectiveness and Safety","year":2023,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biosimilar; Medicine; Adalimumab; Infliximab; Adverse effect; Ulcerative colitis; Inflammatory bowel disease; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03017183,0.001715396,0.006760241,0.01189723,0.0006036797,0.00466995,0.003941661,0.004702403,0.004244216],"category_scores_gemma":[0.08657008,0.001385011,0.005782642,0.01073833,0.001060019,0.005553545,0.002134181,0.00489036,0.001710094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00457667,"about_ca_system_score_gemma":0.01019967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004356676,"about_ca_topic_score_gemma":0.008700821,"domain_scores_codex":[0.9691431,0.007951354,0.01222523,0.001068449,0.009134203,0.0004776145],"domain_scores_gemma":[0.8577336,0.07719123,0.024765,0.002685837,0.0355968,0.002027511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0006629835,0.00008728357,0.0007372334,0.1224411,0.003582758,0.0001895453,0.0002658785,0.0004521086,0.0006691396,0.00205123,0.1233392,0.7455217],"study_design_scores_gemma":[0.0007157711,0.0007255011,0.005954807,0.2307877,0.01360705,0.001241322,0.0002121576,0.0004012509,0.0006548851,0.003015352,0.7425427,0.0001414184],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005688833,0.9807636,0.0006700166,0.009981221,0.003911501,0.0001271799,0.0008768124,0.0001093927,0.002991423],"genre_scores_gemma":[0.009341025,0.9693568,0.00467909,0.009842312,0.003762333,0.0002772562,0.001880328,0.00006932001,0.0007915787],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03017183,"threshold_uncertainty_score":0.1595658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01773202688252754,"score_gpt":0.3134796128733935,"score_spread":0.2957475859908659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}