{"id":"W4387939747","doi":"10.37349/etat.2023.00175","title":"Biomarkers in renal cell carcinoma and their targeted therapies: a review","year":2023,"lang":"en","type":"review","venue":"Exploration of Targeted Anti-tumor Therapy","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Renal cell carcinoma; Targeted therapy; Immunotherapy; Cancer; Biomarker; Kidney cancer; Sunitinib; microRNA; Epigenetics; Bioinformatics; Oncology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007946766,0.0008692808,0.001376173,0.002654036,0.0002997043,0.001194269,0.0007417953,0.001108624,0.00212044],"category_scores_gemma":[0.001018221,0.000253321,0.0007879707,0.002484988,0.000433684,0.001474674,0.0005917414,0.001598984,0.001049463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000612343,"about_ca_system_score_gemma":0.001335106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001059748,"about_ca_topic_score_gemma":0.001437903,"domain_scores_codex":[0.9996653,0.00007973142,0.00006115621,0.00005053635,0.000117068,0.00002631827],"domain_scores_gemma":[0.9994109,0.000290701,0.00009268424,0.0000141392,0.000160285,0.00003141023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001127173,0.00009823633,0.000643933,0.0254867,0.0001714694,0.0004649133,0.000112075,0.0004699746,0.002518593,0.003529976,0.03656201,0.9298295],"study_design_scores_gemma":[0.00001416306,0.0001783352,0.001483573,0.0058561,0.0002713709,0.002724465,0.0001064286,0.0001907944,0.0009073053,0.002012715,0.9862243,0.0000304752],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000127788,0.9985702,0.0001611914,0.0003707485,0.0002850342,0.000005880743,0.0000192094,0.000005649094,0.0004542798],"genre_scores_gemma":[0.0008557071,0.9978938,0.0002837079,0.0002650963,0.000343015,0.00001078525,0.00004073406,0.000001454261,0.0003057263],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002654036,"threshold_uncertainty_score":0.007093549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09424957999287563,"score_gpt":0.32209218553763,"score_spread":0.2278426055447544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}