{"id":"W4387949564","doi":"10.1210/endocr/bqad157","title":"The Power of the Heterogeneous Stock Rat Founder Strains in Modeling Metabolic Disease","year":2023,"lang":"en","type":"article","venue":"Endocrinology","topic":"Birth, Development, and Health","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institute of General Medical Sciences; National Human Genome Research Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Medical College of Wisconsin; National Institutes of Health; Aurora Research Institute","keywords":"Endocrinology; Internal medicine; Population; Biology; Endocrine system; Obesity; Metabolic syndrome; Diabetes mellitus; Hormone; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002265608,0.0009026715,0.0004421603,0.002169247,0.0006415023,0.0006833275,0.0008037638,0.0004938173,0.001477617],"category_scores_gemma":[0.001630144,0.0003877596,0.0004968761,0.0006469045,0.0006062779,0.0004737746,0.000841121,0.001274711,0.0002355087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005478627,"about_ca_system_score_gemma":0.0006507359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006467027,"about_ca_topic_score_gemma":0.01290491,"domain_scores_codex":[0.9987026,0.0005357961,0.0001142132,0.0002669454,0.000269481,0.0001108514],"domain_scores_gemma":[0.9980926,0.0004521812,0.0004559681,0.0005658948,0.000196849,0.0002366251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.004179513,0.002747025,0.07385186,0.000202471,0.0006101825,0.0008769747,0.0006572931,0.004247595,0.8475143,0.008805318,0.001442195,0.05486523],"study_design_scores_gemma":[0.001311756,0.02027774,0.4121188,0.0003922847,0.003106612,0.005851049,0.001504814,0.04436533,0.4556774,0.007741584,0.04722031,0.0004324863],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9605249,0.0008990418,0.03261929,0.0003690303,0.0001165525,0.0004321436,0.001759626,0.0002241848,0.003055291],"genre_scores_gemma":[0.9094528,0.001469653,0.07876445,0.000518719,0.0000711043,0.001538862,0.0024677,0.0002920268,0.005424612],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006467027,"threshold_uncertainty_score":0.01285875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05136785355511544,"score_gpt":0.3250415683174038,"score_spread":0.2736737147622884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}