{"id":"W4387965403","doi":"10.1056/nejmoa2301333","title":"Phase 3 Trial of Nemolizumab in Patients with Prurigo Nodularis","year":2023,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":166,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lynde Centre for Dermatology; University of Toronto","funders":"Galderma","keywords":"Prurigo nodularis; Dermatology; Medicine; Prurigo; Phase (matter); Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001487772,0.0009536943,0.001531139,0.0002371785,0.0004405389,0.0006142755,0.0005592214,0.000985943,0.004993525],"category_scores_gemma":[0.0009600501,0.0003530294,0.001035417,0.0002104861,0.0004677837,0.0004528329,0.0002821683,0.002110529,0.0009112804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005260134,"about_ca_system_score_gemma":0.001277522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005372574,"about_ca_topic_score_gemma":0.001209392,"domain_scores_codex":[0.9996195,0.0002057714,0.00002090621,0.00004917885,0.00003581743,0.00006878333],"domain_scores_gemma":[0.9994679,0.0001147192,0.0001378252,0.00003881539,0.000042951,0.0001977876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8799714,0.02506431,0.004820059,0.001004985,0.001230256,0.0003051968,0.0001906842,0.000997462,0.02307615,0.0002857291,0.004613038,0.05844067],"study_design_scores_gemma":[0.8870742,0.103024,0.00630742,0.00004019103,0.0001921736,0.0001732991,0.00002289856,0.000424768,0.0008512857,0.0001285255,0.001749276,0.00001204053],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860386,0.003626862,0.0007225882,0.001094642,0.0002403944,0.004850083,0.001183915,0.0001255759,0.002117479],"genre_scores_gemma":[0.9825775,0.001731514,0.001911937,0.001990607,0.0002539206,0.007483507,0.001724727,0.00002737511,0.002298941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004993525,"threshold_uncertainty_score":0.01670504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01456288797405011,"score_gpt":0.2994124749713206,"score_spread":0.2848495869972705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}