{"id":"W4388009503","doi":"10.1016/j.heliyon.2023.e21408","title":"Proof of concept: Pull down assay using bovine serum albumin and an immunomodulator small molecule","year":2023,"lang":"en","type":"article","venue":"Heliyon","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates; Alberta Cancer Foundation","keywords":"Bovine serum albumin; Albumin; Chemistry; Serum albumin; Computational biology; Medicine; Biochemistry; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003081349,0.0001400195,0.0002984008,0.0001378304,0.00007486019,0.00001550727,0.00008877469,0.00008585268,0.0001744736],"category_scores_gemma":[0.00007019784,0.0001127609,0.00006340588,0.0002810135,0.0001446777,0.00006130814,0.0001229316,0.0001765,0.00002060442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002433965,"about_ca_system_score_gemma":0.0001035543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002346765,"about_ca_topic_score_gemma":0.00003840886,"domain_scores_codex":[0.9987873,0.0000759973,0.0002482804,0.0002562807,0.0002929541,0.0003391595],"domain_scores_gemma":[0.9993367,0.00005683781,0.00005910842,0.0002408247,0.0001243176,0.0001822428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001020026,0.0003112805,0.03727424,0.002142156,0.0001724337,0.0003139378,0.001001171,0.00003595819,0.9336561,0.0005594087,0.0003889297,0.02312436],"study_design_scores_gemma":[0.002435395,0.002569088,0.1304027,0.001089062,0.0001062208,0.0002255334,0.0003953788,0.01683282,0.8370293,0.0001241569,0.008360969,0.0004293483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956744,0.002263454,0.00006257974,0.0007482288,0.00006796529,0.0003173545,0.00006197199,0.0000414593,0.0007625733],"genre_scores_gemma":[0.994007,0.0002609729,0.0005147599,0.0001685508,0.0001782932,0.000007492407,0.00008296667,0.00002831478,0.00475168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09662681,"threshold_uncertainty_score":0.4598256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04857749706934232,"score_gpt":0.3340405651451509,"score_spread":0.2854630680758086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}