{"id":"W4388014770","doi":"10.1111/hae.14882","title":"Indirect treatment comparisons of the gene therapy etranacogene dezaparvovec versus extended half‐life factor IX therapies for severe or moderately severe haemophilia B","year":2023,"lang":"en","type":"article","venue":"Haemophilia","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"EVERSANA (Canada)","funders":"CSL Behring","keywords":"Medicine; Haemophilia B; Haemophilia; Placebo; Haemophilia A; Odds ratio; Internal medicine; Clinical trial; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01247753,0.0008513193,0.001822355,0.0005167765,0.0001304629,0.0008702016,0.0005563667,0.0007740938,0.008435713],"category_scores_gemma":[0.0140184,0.000258489,0.003322582,0.0004324692,0.0005631845,0.000623799,0.0006491226,0.001937139,0.000559061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005723747,"about_ca_system_score_gemma":0.0005116292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003578961,"about_ca_topic_score_gemma":0.00040531,"domain_scores_codex":[0.9857232,0.01206364,0.000526277,0.0005786673,0.000887877,0.0002202608],"domain_scores_gemma":[0.9855181,0.01047398,0.002379483,0.0007779878,0.0004167861,0.0004336353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.8783211,0.001664078,0.006243211,0.002693312,0.01733088,0.00004540675,0.0001519613,0.003150887,0.003699209,0.001805319,0.001576123,0.08331855],"study_design_scores_gemma":[0.2902963,0.5559108,0.072616,0.001136941,0.03600739,0.0004028064,0.0001982863,0.009324747,0.01215267,0.005213186,0.01659788,0.0001430899],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.950835,0.02034144,0.007345644,0.0007280813,0.0006975752,0.003450501,0.004084458,0.0001237025,0.01239364],"genre_scores_gemma":[0.9877697,0.002367079,0.003593191,0.0002695889,0.0001418534,0.001910977,0.001053162,0.00002119577,0.002873214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01247753,"threshold_uncertainty_score":0.0659883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1709719193391946,"score_gpt":0.3664104514239779,"score_spread":0.1954385320847833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}