{"id":"W4388036682","doi":"10.1016/j.jtct.2023.10.018","title":"Donor-Derived Malignancy and Transplantation Morbidity: Risks of Patient and Donor Genetics in Allogeneic Hematopoietic Stem Cell Transplantation","year":2023,"lang":"en","type":"review","venue":"Transplantation and Cellular Therapy","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; Office of Naval Research; National Heart, Lung, and Blood Institute; Genentech; Health Resources and Services Administration; Swedish Orphan Biovitrum; National Institute of Environmental Health Sciences; Servier; Gateway for Cancer Research; Astellas Pharma; Sanofi; MacroGenics; Incyte; Leukemia and Lymphoma Society","keywords":"Hematopoietic stem cell transplantation; Medicine; Transplantation; Genetic testing; Germline; Oncology; CEBPA; Immunology; Internal medicine; Genetics; Biology; Mutation; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001401501,0.0007251971,0.001727479,0.001364604,0.0001990244,0.001292352,0.00102949,0.001397573,0.002835047],"category_scores_gemma":[0.00233853,0.0002436834,0.0006859485,0.001769649,0.000599749,0.001226377,0.000790518,0.002224068,0.0006733789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008085473,"about_ca_system_score_gemma":0.001653815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001451226,"about_ca_topic_score_gemma":0.003935927,"domain_scores_codex":[0.9996436,0.0001113047,0.00005157819,0.00005798583,0.0001123721,0.00002317968],"domain_scores_gemma":[0.9981117,0.001427853,0.0001840899,0.00001999748,0.000191505,0.00006493893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001267535,0.00004166841,0.0004742177,0.01561763,0.0002542369,0.0001463191,0.00004816704,0.000343183,0.0003241957,0.003816928,0.03612386,0.9426829],"study_design_scores_gemma":[0.00008413419,0.000141509,0.002832345,0.02481792,0.001104624,0.001399409,0.0001595347,0.0002532821,0.0002158826,0.005449271,0.9634836,0.00005837188],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003200556,0.9994079,0.00003357642,0.0002592217,0.0001125779,5.909386e-7,0.000004858391,0.000001300207,0.0001479063],"genre_scores_gemma":[0.0004301908,0.9987531,0.00007441272,0.0003285173,0.0003039079,0.000001616252,0.000009848766,6.914498e-7,0.00009769109],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002835047,"threshold_uncertainty_score":0.009484112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09424667534191573,"score_gpt":0.3399268667014665,"score_spread":0.2456801913595508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}