{"id":"W4388040303","doi":"10.1002/pro.4823","title":"Site‐specific photo‐crosslinking/cleavage for protein–protein interface identification reveals oligomeric assembly of lysosomal‐associated membrane protein type 2A in mammalian cells","year":2023,"lang":"en","type":"article","venue":"Protein Science","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovation Cluster (Canada)","funders":"Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Japan Agency for Medical Research and Development; University Fellowship Creation Project for Creating Scientific and Technological Innovation","keywords":"Cleavage (geology); Cell biology; Chemistry; Biophysics; Membrane; Membrane protein; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002312459,0.0002883335,0.0003422854,0.0003140868,0.0002302595,0.0001201327,0.0007211966,0.0002525093,0.00002251462],"category_scores_gemma":[0.0003014768,0.0003006021,0.0001348893,0.001946101,0.0003957488,0.00004623784,0.0001326511,0.0001814483,0.00004848453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009083154,"about_ca_system_score_gemma":0.0002171939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001328976,"about_ca_topic_score_gemma":0.0001104935,"domain_scores_codex":[0.9969089,0.0001062642,0.0007566305,0.0009638317,0.0005830001,0.0006813977],"domain_scores_gemma":[0.998334,0.000008227369,0.0004588976,0.0006528493,0.0004201499,0.0001258873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002156452,0.0001121249,0.0002167658,0.0002122524,0.000006996397,0.000004859131,0.000203868,0.00006382548,0.9984462,0.0001121817,0.0000174773,0.0003878442],"study_design_scores_gemma":[0.0006749374,0.0003599965,0.00243651,0.000264668,0.000007504653,0.000001050562,0.00008361765,0.0003212162,0.9930983,0.0002871533,0.002123052,0.0003419784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911209,0.0002255312,0.003552716,0.0001114351,0.0001340492,0.004590809,0.00005737858,0.00006087941,0.0001463313],"genre_scores_gemma":[0.9940919,0.00002008344,0.001069329,0.00001449563,0.00006730735,0.000759645,0.0004976373,0.00004770057,0.00343192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005347844,"threshold_uncertainty_score":0.9999446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01865871699514068,"score_gpt":0.2689359891294682,"score_spread":0.2502772721343275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}