{"id":"W4388047823","doi":"10.1136/jitc-2023-sitc2023.0985","title":"985 PSGL-1 is a novel inhibitor of tumor cell phagocytosis by macrophages","year":2023,"lang":"en","type":"article","venue":"Regular and Young Investigator Award Abstracts","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Phagocytosis; Macrophage; Cell biology; Biology; Immune system; Molecular biology; Myeloid; Chemistry; Immunology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003934937,0.0003411706,0.0005242084,0.0001976447,0.0002269253,0.00004338931,0.0002281904,0.0002945916,0.000072867],"category_scores_gemma":[0.0001103932,0.0002858756,0.0001698034,0.0003887528,0.0005300591,0.0002434635,0.0001286042,0.0002925797,0.0002422804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003876468,"about_ca_system_score_gemma":0.0001502817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002015389,"about_ca_topic_score_gemma":0.000003361188,"domain_scores_codex":[0.9980941,0.00008065363,0.000654487,0.0005043524,0.0001335088,0.0005328698],"domain_scores_gemma":[0.9989167,0.00008120398,0.0003559142,0.0004012114,0.00009884666,0.0001460819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003856382,0.0001236847,0.002715919,0.0001552003,0.0001051005,0.000004634636,0.0004365976,0.000008323023,0.9376642,0.00006800072,0.05820692,0.0004728776],"study_design_scores_gemma":[0.001491362,0.0001309905,0.03312024,0.0001158896,0.00008461712,0.00005809993,0.000184973,0.00003206875,0.9246655,0.0001406176,0.03966008,0.0003155512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933106,0.004148836,0.00001922251,0.0007519402,0.0006969309,0.0002795679,0.0003214744,0.000156156,0.000315296],"genre_scores_gemma":[0.9944292,0.0002872021,0.0001305302,0.0003236661,0.00005951063,0.00002514937,0.000310246,0.00004885791,0.004385691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03040432,"threshold_uncertainty_score":0.9999593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01305545456517759,"score_gpt":0.2248091643832972,"score_spread":0.2117537098181196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}