{"id":"W4388071235","doi":"10.1136/jitc-2023-sitc2023.1490","title":"1490 High-plex co-detection of RNA and protein to explore tumor-immune interactions utilizing RNAscope with imaging mass cytometry","year":2023,"lang":"en","type":"article","venue":"Regular and Young Investigator Award Abstracts","topic":"Advanced Biosensing Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Standards Association","funders":"","keywords":"Mass cytometry; RNA; Biology; Molecular biology; Computational biology; Phenotype; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001627234,0.0001747355,0.0001755184,0.0001345054,0.0001614803,0.00004569298,0.00008337243,0.00005771551,8.839414e-7],"category_scores_gemma":[0.0001102446,0.0001621076,0.00003555038,0.0002823254,0.0001910356,0.00002126384,0.00007292729,0.0001241199,0.000002803973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001670535,"about_ca_system_score_gemma":0.00004738222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006475546,"about_ca_topic_score_gemma":0.00001170875,"domain_scores_codex":[0.9990134,0.00002203428,0.0002498193,0.0003654568,0.0001295745,0.0002196901],"domain_scores_gemma":[0.9992592,0.000009889165,0.0001408978,0.0002971136,0.00009217974,0.0002006612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003482036,0.00001248916,0.0004043077,0.00004603395,0.00002212339,0.00000747654,0.00004885203,0.00003332374,0.9978775,0.00005915844,0.0001763447,0.001277504],"study_design_scores_gemma":[0.0002074157,0.0001223904,0.01111635,0.0001499253,0.00001869115,0.00006782868,0.0003602262,0.0000704601,0.9821001,0.0003593121,0.005229033,0.0001982777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948221,0.0001463402,0.003932912,0.0004425555,0.00004132062,0.0003753429,0.00001915864,0.00009682955,0.000123416],"genre_scores_gemma":[0.9917896,0.00005550801,0.007683929,0.00008490077,0.00007130112,0.00006195944,0.00006163844,0.00003573499,0.0001554493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01577747,"threshold_uncertainty_score":0.6610556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01845165894724315,"score_gpt":0.2781303994629118,"score_spread":0.2596787405156686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}