{"id":"W4388074293","doi":"10.1016/j.jtho.2023.09.904","title":"EP06.03-12 Characteristics, Treatment Patterns and Outcomes of Real-World NSCLC Exon 20 Insertions in HER1 (EGFR) and HER2 (ERBB2)","year":2023,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Health Services; Calgary Laboratory Services; University of Calgary","funders":"","keywords":"Medicine; Exon; Oncology; Internal medicine; Genetics; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004675671,0.000142521,0.0001733559,0.000549542,0.0002677617,0.0006612839,0.0003501616,0.0005275295,0.00684511],"category_scores_gemma":[0.002436071,0.0001299333,0.0003846954,0.001056995,0.0002714583,0.0006083252,0.0004101205,0.0004536361,0.001126155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003422913,"about_ca_system_score_gemma":0.0003330031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003656907,"about_ca_topic_score_gemma":0.003751817,"domain_scores_codex":[0.9996779,0.00005378568,0.00005720532,0.00008751083,0.00003860804,0.00008495506],"domain_scores_gemma":[0.9985473,0.0003394812,0.0005910102,0.00008810029,0.000181391,0.0002527313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004337386,0.00006828627,0.9953491,0.00001828112,0.00004648475,0.0001582136,0.00005148666,0.0002286581,0.0002129099,0.00007105085,0.001193688,0.0021681],"study_design_scores_gemma":[0.00001728044,0.000130465,0.9979053,0.00001035307,0.00001662888,0.0004600259,0.0001687174,0.0002298203,0.00007377638,0.00006891407,0.0009112548,0.000007616924],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893612,0.0001404859,0.00009840857,0.00009785436,0.00001315078,0.00001119281,0.008917563,0.000006700039,0.001353266],"genre_scores_gemma":[0.9916422,0.0000616913,0.00005088933,0.00007074717,0.00001353844,0.0000190896,0.007248493,0.000007911682,0.0008852978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00684511,"threshold_uncertainty_score":0.02289921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03609877914508521,"score_gpt":0.4449655504943838,"score_spread":0.4088667713492986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}