{"id":"W4388074411","doi":"10.3390/cancers15215229","title":"CD47: The Next Frontier in Immune Checkpoint Blockade for Non-Small Cell Lung Cancer","year":2023,"lang":"en","type":"review","venue":"Cancers","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Cancer Research Society; Canada Research Chairs; International Association for the Study of Lung Cancer","keywords":"Blockade; Immune checkpoint; CD47; Lung cancer; Immunotherapy; Medicine; Immune system; Immunology; Cancer; Cancer immunotherapy; Cancer research; Ipilimumab; Oncology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005215627,0.0006180162,0.001000971,0.001370073,0.0002037801,0.0007120934,0.000620498,0.0009667322,0.002294677],"category_scores_gemma":[0.0004266955,0.0002037653,0.0004653887,0.001200663,0.0003818879,0.001315932,0.0004995246,0.002495374,0.001639458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005574001,"about_ca_system_score_gemma":0.0007980654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006202215,"about_ca_topic_score_gemma":0.001392811,"domain_scores_codex":[0.9998729,0.00002400761,0.00001451756,0.00001743027,0.00005378396,0.00001737362],"domain_scores_gemma":[0.9998313,0.00007626566,0.00002211551,0.000005702478,0.00004400493,0.00002055342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009184772,0.00007514653,0.0001036107,0.009810507,0.00006099763,0.0001460132,0.00003749392,0.0003336821,0.002994739,0.004204029,0.03651751,0.9456244],"study_design_scores_gemma":[0.00002235951,0.0001255906,0.0004879799,0.001884786,0.00005576919,0.0008322041,0.00003061684,0.00008436378,0.0005851089,0.001831354,0.9940485,0.00001147059],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009946955,0.9986421,0.0001160992,0.0003400556,0.0002204548,0.000003732383,0.00001047957,0.000006637494,0.0005609724],"genre_scores_gemma":[0.0005530927,0.9982838,0.0001416639,0.0002764716,0.0001936569,0.00000585875,0.00002088581,0.000001446391,0.0005231533],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002294677,"threshold_uncertainty_score":0.007676482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05194838538533705,"score_gpt":0.3150092726455423,"score_spread":0.2630608872602053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}