{"id":"W4388074411","doi":"10.3390/cancers15215229","title":"CD47: The Next Frontier in Immune Checkpoint Blockade for Non-Small Cell Lung Cancer","year":2023,"lang":"en","type":"review","venue":"Cancers","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Cancer Research Society; Canada Research Chairs; International Association for the Study of Lung Cancer","keywords":"Blockade; Immune checkpoint; CD47; Lung cancer; Immunotherapy; Medicine; Immune system; Immunology; Cancer; Cancer immunotherapy; Cancer research; Ipilimumab; Oncology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000436867,0.0004810284,0.001532953,0.0001989009,0.0001981262,0.00003547991,0.0006229752,0.0006629808,0.000191013],"category_scores_gemma":[0.00003365377,0.0003335182,0.0007488552,0.0003922427,0.0001408347,0.00006942526,0.0001394501,0.0006534242,0.0001304857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001892127,"about_ca_system_score_gemma":0.001758446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001753581,"about_ca_topic_score_gemma":0.0003568406,"domain_scores_codex":[0.9977323,0.0001729508,0.0008890473,0.0005276949,0.00003804294,0.0006399884],"domain_scores_gemma":[0.9985576,0.0002274875,0.0005631158,0.0005752647,0.00005579511,0.00002076501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001011294,0.00004326183,0.00002434881,0.0188163,0.001660326,0.000003943869,0.001071269,0.0002364201,0.004822619,0.00003512084,0.02684762,0.9463376],"study_design_scores_gemma":[0.0008970263,0.00003485146,0.00005410932,0.006155411,0.0007820709,0.000004402061,0.0001276076,0.00008283225,0.001401623,0.00001148824,0.9900413,0.0004072983],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003326097,0.993188,0.00005196603,0.00007616876,0.00343809,0.002415224,0.000181133,0.00004798381,0.0002688833],"genre_scores_gemma":[0.0002318085,0.9835561,0.00001753671,0.00003754146,0.0002077063,0.002824441,0.0004473236,0.0001088902,0.01256866],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9631937,"threshold_uncertainty_score":0.9999117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05194838538533705,"score_gpt":0.3150092726455423,"score_spread":0.2630608872602053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}