{"id":"W4388084579","doi":"10.1101/2023.10.30.564690","title":"Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Queen's University; Queen's University Belfast","keywords":"Biology; RNA-binding protein; RNA; Nuclear export signal; Cell biology; Messenger RNA; RNA splicing; Influenza A virus; Interactome; Gene; Genetics; Virus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001211714,0.0002112777,0.0001592031,0.0002319088,0.0001875348,0.0003048291,0.0001783004,0.0003010463,0.00153513],"category_scores_gemma":[0.0001423171,0.0001527027,0.0001801487,0.0001364582,0.0001973353,0.0001803842,0.0002824986,0.0003587296,0.0009988296],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003012185,"about_ca_system_score_gemma":0.0001183462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006188163,"about_ca_topic_score_gemma":0.0008287201,"domain_scores_codex":[0.9999201,0.000009010615,0.00000464574,0.00002487156,0.00001836862,0.0000229451],"domain_scores_gemma":[0.9999428,0.00001279247,0.000009323676,0.00001030468,0.000009076072,0.0000157157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001054202,0.00000544068,0.0006281052,0.0000152118,0.000002370507,0.00004977685,0.00001544834,0.00003557798,0.9985119,0.00008142863,0.0000415517,0.0005077035],"study_design_scores_gemma":[0.00001202925,0.0001168404,0.0411766,0.000007106898,0.00001547007,0.0008634388,0.0000954778,0.004425145,0.9490553,0.0002361967,0.003988855,0.000007484121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901167,0.001345332,0.005197476,0.0001419037,0.00003298269,0.00001615227,0.0005979686,0.00008189088,0.002469737],"genre_scores_gemma":[0.9881534,0.0004208108,0.004693376,0.000079462,0.00001528965,0.00002230056,0.001566935,0.00004633015,0.005002004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00153513,"threshold_uncertainty_score":0.005135477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02301168735856002,"score_gpt":0.2648593150100419,"score_spread":0.2418476276514819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}