{"id":"W4388087237","doi":"10.1136/jitc-2023-sitc2023.0839","title":"839 TALL<sup>TM</sup> (Targeted Antigen Loaded Liposomes) immunotherapy exploits recall immunity to form an excellent co-therapy option for immune checkpoint inhibitors","year":2023,"lang":"en","type":"article","venue":"Regular and Young Investigator Award Abstracts","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Oncolytic virus; Immunotherapy; Adoptive cell transfer; Tumor microenvironment; Medicine; Cancer research; Chimeric antigen receptor; Cancer; Immune system; Tumor-infiltrating lymphocytes; Antigen; Immunology; T cell; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001293074,0.0003336682,0.0001502288,0.000194068,0.000130234,0.0003580509,0.0001875494,0.0003422319,0.003262001],"category_scores_gemma":[0.00005786685,0.0001352105,0.0002338503,0.00009956032,0.0001621242,0.0002781078,0.0002468247,0.0004957632,0.001365122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002832931,"about_ca_system_score_gemma":0.0002182161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003912801,"about_ca_topic_score_gemma":0.0006156904,"domain_scores_codex":[0.9999189,0.00001007611,0.000006780163,0.00001619443,0.00002579889,0.00002227319],"domain_scores_gemma":[0.9999615,0.000004295244,0.00001173487,0.000004733392,0.000008243892,0.000009561595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009997965,0.00003463194,0.0001952705,0.00004285877,0.000004715145,0.00003413601,0.000006739374,0.0001327076,0.994625,0.0002656784,0.0003263393,0.004231885],"study_design_scores_gemma":[0.0000120304,0.0002309301,0.000841913,0.000005688018,0.000007805847,0.0001394673,0.000007781661,0.0007259887,0.9915423,0.00007174824,0.006409924,0.000004314013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9330011,0.004152669,0.04671487,0.0007693254,0.0002080196,0.0002970216,0.002377218,0.0009230123,0.01155676],"genre_scores_gemma":[0.9553117,0.001894242,0.02517466,0.0003741109,0.00003844767,0.0001963642,0.002471514,0.0001332391,0.01440567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003262001,"threshold_uncertainty_score":0.01091254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04654766558957397,"score_gpt":0.313102187007151,"score_spread":0.2665545214175771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}