{"id":"W4388087237","doi":"10.1136/jitc-2023-sitc2023.0839","title":"839 TALL<sup>TM</sup> (Targeted Antigen Loaded Liposomes) immunotherapy exploits recall immunity to form an excellent co-therapy option for immune checkpoint inhibitors","year":2023,"lang":"en","type":"article","venue":"Regular and Young Investigator Award Abstracts","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Oncolytic virus; Immunotherapy; Adoptive cell transfer; Tumor microenvironment; Medicine; Cancer research; Chimeric antigen receptor; Cancer; Immune system; Tumor-infiltrating lymphocytes; Antigen; Immunology; T cell; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002358448,0.0007060742,0.001011338,0.0007150177,0.0005440218,0.000241129,0.0004409592,0.0005169459,0.0002296829],"category_scores_gemma":[0.0004010424,0.0006634647,0.0004830379,0.0008947821,0.0003749311,0.0005215317,0.0001214244,0.0007093977,0.0001318118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003783657,"about_ca_system_score_gemma":0.0005402152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006228223,"about_ca_topic_score_gemma":0.00001983892,"domain_scores_codex":[0.995191,0.0002254908,0.001244882,0.0009830808,0.001061355,0.001294196],"domain_scores_gemma":[0.9963422,0.000159791,0.0002835775,0.001268542,0.0004104642,0.001535409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001960432,0.0004022637,0.001311863,0.0002183944,0.0003879671,0.00007412465,0.005316041,0.00023515,0.9735155,0.0000387781,0.001505557,0.01503397],"study_design_scores_gemma":[0.006452951,0.002259215,0.04638495,0.000355479,0.00004544573,0.0001385555,0.00166239,0.001111344,0.8813077,0.0006821412,0.05881223,0.0007876646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990589,0.001714503,0.00006580574,0.002723815,0.0003898229,0.003660423,0.00007181225,0.0005539064,0.0002309233],"genre_scores_gemma":[0.9873834,0.004455814,0.001324584,0.0006842374,0.0006831393,0.00052403,0.00106463,0.000291647,0.003588524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09220782,"threshold_uncertainty_score":0.9995816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04654766558957397,"score_gpt":0.313102187007151,"score_spread":0.2665545214175771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}