{"id":"W4388128900","doi":"10.1038/s41396-023-01545-3","title":"Coordinated proteome change precedes cell lysis and death in a mat-forming cyanobacterium","year":2023,"lang":"en","type":"article","venue":"The ISME Journal","topic":"Microbial Community Ecology and Physiology","field":"Environmental Science","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Innovates; Canada First Research Excellence Fund; Government of Alberta; Genome Canada","keywords":"Biology; Programmed cell death; Cyanobacteria; Lysis; Proteome; Metaproteomics; Microbiology; Cell biology; Metagenomics; Apoptosis; Biochemistry; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001279334,0.0001798727,0.0002682428,0.0001802618,0.0002085529,0.0003339343,0.0001500852,0.0002882523,0.0005995167],"category_scores_gemma":[0.0002203814,0.0001246156,0.0001788998,0.0002318203,0.0002169611,0.0002792133,0.0003381048,0.0004491356,0.0002014424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002758079,"about_ca_system_score_gemma":0.000228935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001300105,"about_ca_topic_score_gemma":0.001294159,"domain_scores_codex":[0.9999009,0.000006556393,0.000006071617,0.0000322295,0.00003120253,0.00002301564],"domain_scores_gemma":[0.9998429,0.00002248015,0.00005064043,0.00001074023,0.00002713916,0.00004599186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000107811,0.000009703575,0.002971713,0.00001715723,0.000004699095,0.00006032478,0.00003634888,0.00003306515,0.9962195,0.00001999327,0.00001987578,0.0004997218],"study_design_scores_gemma":[0.0000110733,0.0004027438,0.4124756,0.00001002932,0.00002404649,0.0004276619,0.0004151811,0.001794175,0.5831683,0.0001680127,0.001083581,0.00001962215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997666,0.0002989182,0.0007811622,0.00006753043,0.00001007565,0.000008361203,0.0007727162,0.00002088291,0.0003743404],"genre_scores_gemma":[0.9975032,0.0001545916,0.0008214691,0.00008073451,0.000004932705,0.00001907865,0.0008053135,0.000009384084,0.0006013607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001300105,"threshold_uncertainty_score":0.002585053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03123899090461651,"score_gpt":0.2446546329253914,"score_spread":0.2134156420207749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}