{"id":"W4388133624","doi":"10.1111/mmi.15172","title":"Molecular regulation of virulence in <i>Legionella pneumophila</i>","year":2023,"lang":"en","type":"review","venue":"Molecular Microbiology","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Legionella pneumophila; Biology; Virulence; Legionella; Intracellular parasite; Microbiology; Effector; Intracellular; Secretion; Bacteria; Pathogen; Legionnaires' disease; Pathogenicity island; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004527234,0.0005513366,0.001379485,0.0004952144,0.0000390254,0.00001600734,0.0007986663,0.00111347,0.000006155066],"category_scores_gemma":[0.0001244005,0.0005238141,0.0006416535,0.0007495471,0.0003237529,0.000003388772,0.0005516221,0.0004445047,0.0001216827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000584404,"about_ca_system_score_gemma":0.0003725161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003798618,"about_ca_topic_score_gemma":0.00001857085,"domain_scores_codex":[0.996688,0.0005280456,0.0009604885,0.001030647,0.0001384898,0.0006543194],"domain_scores_gemma":[0.9983527,0.00004652321,0.0004160094,0.0009689812,0.0001193659,0.00009640948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002694275,0.00008491093,0.000007536976,0.00384304,0.0002107864,0.0001724051,0.00001140384,0.00006613642,0.9649951,0.0003498266,0.000723493,0.02950844],"study_design_scores_gemma":[0.0004282562,0.0002175587,0.000003466423,0.002434308,0.0001457536,0.0002282309,0.000007555851,0.000006421629,0.08323251,0.0001445314,0.912492,0.0006593679],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00766536,0.9903558,0.0002006018,0.00004888231,0.0002185895,0.0009217553,0.0001293078,0.00002561827,0.0004340218],"genre_scores_gemma":[0.01072646,0.9865499,0.000104557,0.0001053848,0.00009224591,0.0001185327,0.001824353,0.0001507963,0.0003277549],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9117686,"threshold_uncertainty_score":0.9997213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02741365418437189,"score_gpt":0.3140143732779552,"score_spread":0.2866007190935833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}