{"id":"W4388133624","doi":"10.1111/mmi.15172","title":"Molecular regulation of virulence in <i>Legionella pneumophila</i>","year":2023,"lang":"en","type":"review","venue":"Molecular Microbiology","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Legionella pneumophila; Biology; Virulence; Legionella; Intracellular parasite; Microbiology; Effector; Intracellular; Secretion; Bacteria; Pathogen; Legionnaires' disease; Pathogenicity island; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002454682,0.0007370338,0.0007135077,0.001295648,0.0002390043,0.0007789432,0.0005728924,0.0008401801,0.002462467],"category_scores_gemma":[0.0002704905,0.0002327461,0.0003203407,0.001539916,0.0003465014,0.00102108,0.000498377,0.001101578,0.002291339],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006781016,"about_ca_system_score_gemma":0.0008008326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007960094,"about_ca_topic_score_gemma":0.001130912,"domain_scores_codex":[0.9999206,0.00001032346,0.000009125097,0.00001679951,0.00003098997,0.00001207045],"domain_scores_gemma":[0.9999167,0.00002605733,0.00001494961,0.000003941286,0.00002443016,0.00001402138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001011493,0.00006310981,0.0001629468,0.01621079,0.00006178759,0.000267409,0.00007841815,0.0006195639,0.01504514,0.008751461,0.03257593,0.9260623],"study_design_scores_gemma":[0.000009409406,0.00007911233,0.0005948876,0.001231799,0.00003829682,0.0005158319,0.00003023654,0.00007100462,0.001687105,0.001646452,0.9940832,0.00001265581],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002190071,0.9971,0.0001697214,0.0002155235,0.0002263517,0.000004440275,0.00002320878,0.00001220573,0.002029662],"genre_scores_gemma":[0.0008645151,0.9974195,0.0001909795,0.0001468113,0.00009465638,0.000006280558,0.00004401087,0.000001814177,0.001231415],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002462467,"threshold_uncertainty_score":0.008237779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02741365418437189,"score_gpt":0.3140143732779552,"score_spread":0.2866007190935833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}