{"id":"W4388142123","doi":"10.1136/bcr-2023-256125","title":"Pembrolizumab-induced immune-related sclerosing cholangitis","year":2023,"lang":"en","type":"article","venue":"BMJ Case Reports","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre; Juravinski Hospital; Juravinski Cancer Centre","funders":"","keywords":"Ursodeoxycholic acid; Pembrolizumab; Medicine; Prednisone; Adverse effect; Immunotherapy; Immune system; Internal medicine; Gastroenterology; Cancer; Dermatology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003428622,0.0007935892,0.0009054599,0.001147297,0.001316004,0.0008291965,0.0003508432,0.001788794,0.003589544],"category_scores_gemma":[0.001470143,0.0003717388,0.000799422,0.000773672,0.001044579,0.001112109,0.0006432615,0.002143892,0.001067127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008057998,"about_ca_system_score_gemma":0.00060163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001440733,"about_ca_topic_score_gemma":0.001792087,"domain_scores_codex":[0.9994646,0.0001277559,0.00005301195,0.00007215897,0.00008445101,0.0001980418],"domain_scores_gemma":[0.9991359,0.0002830635,0.0002862112,0.00007851399,0.00004621453,0.0001700761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00007164827,0.00004808691,0.01061235,0.0001436681,0.00002203279,0.9802082,0.0001297797,0.00008267107,0.001640625,0.0004899133,0.0006908349,0.005860258],"study_design_scores_gemma":[0.00003526906,0.00008113048,0.005666495,0.00004994082,0.00002268906,0.9893162,0.00008734447,0.0002698964,0.0008774673,0.0002500456,0.003335619,0.000007880533],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8718217,0.04404913,0.006821576,0.009216828,0.0007177063,0.0003528255,0.0003137162,0.0005381255,0.06616847],"genre_scores_gemma":[0.9856842,0.006303323,0.001055879,0.002432488,0.0009411294,0.0000325569,0.0001006092,0.00002675933,0.003423252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003589544,"threshold_uncertainty_score":0.01200819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04648718999545944,"score_gpt":0.3259309511375578,"score_spread":0.2794437611420983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}