{"id":"W4388142123","doi":"10.1136/bcr-2023-256125","title":"Pembrolizumab-induced immune-related sclerosing cholangitis","year":2023,"lang":"en","type":"article","venue":"BMJ Case Reports","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre; Juravinski Hospital; Juravinski Cancer Centre","funders":"","keywords":"Ursodeoxycholic acid; Pembrolizumab; Medicine; Prednisone; Adverse effect; Immunotherapy; Immune system; Internal medicine; Gastroenterology; Cancer; Dermatology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004338025,0.0001612823,0.0003078588,0.0001645837,0.000223044,0.00004303801,0.00002797673,0.0001154583,0.0004164109],"category_scores_gemma":[0.000323718,0.000148023,0.0002421189,0.0005305802,0.00003752669,0.0001387292,0.0001035048,0.0002366132,0.0003012758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006548261,"about_ca_system_score_gemma":0.0002000802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008466336,"about_ca_topic_score_gemma":0.000004141918,"domain_scores_codex":[0.9984329,0.00005309456,0.0005882329,0.0002885313,0.0002931177,0.0003441532],"domain_scores_gemma":[0.998621,0.00004052864,0.0002160839,0.0007722913,0.0001200079,0.0002300193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00006756071,0.0001130982,0.01513554,0.0001128882,0.0001627671,0.9529812,0.00032241,0.00000465661,0.0220202,0.00002049577,0.001930908,0.007128313],"study_design_scores_gemma":[0.001061529,0.0001264607,0.3815257,0.0003135619,0.0002201584,0.6120178,0.0003410587,0.0002415326,0.002867592,0.00008739729,0.0009820015,0.0002152293],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905093,0.0002879066,0.000001896737,0.0002906274,0.0005861806,0.0005997317,0.000005165696,0.000458839,0.007260406],"genre_scores_gemma":[0.9973612,0.00004658752,0.00002424684,0.00009673339,0.0001330433,0.00003490801,0.0001398282,0.0000424992,0.002120932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3663902,"threshold_uncertainty_score":0.6036202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04648718999545944,"score_gpt":0.3259309511375578,"score_spread":0.2794437611420983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}