{"id":"W4388161805","doi":"10.3390/v15112171","title":"HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing","year":2023,"lang":"en","type":"article","venue":"Viruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakehead University","funders":"National Institute of Allergy and Infectious Diseases; National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institutes of Health; National Cancer Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Provirus; Gene silencing; Latency (audio); Virology; Human immunodeficiency virus (HIV); Biology; Antiretroviral therapy; Medicine; Computational biology; Computer science; Viral load; Genetics; Genome; Gene; Telecommunications","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002155826,0.0001151202,0.0001202406,0.00007463543,0.0004821546,0.0000340739,0.0002195203,0.0000635309,0.00108655],"category_scores_gemma":[0.0001443539,0.00006787162,0.00004914693,0.0002320823,0.00005095591,0.00005420048,0.0001862661,0.0001757236,0.0413077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003825452,"about_ca_system_score_gemma":0.00006022399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008359568,"about_ca_topic_score_gemma":0.00000915482,"domain_scores_codex":[0.9990357,0.0001302551,0.0001465863,0.000222597,0.00005610468,0.0004087375],"domain_scores_gemma":[0.9993934,0.0002233934,0.00002715618,0.0002829491,0.00002820202,0.00004490306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005521223,0.00004965996,0.007325871,0.00001288955,0.00008255164,0.00006152947,0.001889793,0.00003117898,0.7002766,0.0001825134,0.2796848,0.0103474],"study_design_scores_gemma":[0.0008967901,0.0002287262,0.02568617,0.0001244025,0.00002518531,0.00004538341,0.002656021,0.00001836571,0.317452,0.00005317893,0.6525667,0.0002471592],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916504,0.0008617299,0.00001903778,0.00302741,0.0002547149,0.000300564,0.000152157,0.0002092588,0.003524754],"genre_scores_gemma":[0.9894025,0.000121307,0.00004750267,0.0008179226,0.0000797598,0.00009085453,0.0001403902,0.00001568462,0.009284033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3828246,"threshold_uncertainty_score":0.9998266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05757780199956345,"score_gpt":0.3122395210225776,"score_spread":0.2546617190230142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}