{"id":"W4388178153","doi":"10.21203/rs.3.rs-3473160/v1","title":"Mismatch repair genes as prognosis biomarkers for hepatocellular carcinoma","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Ferroptosis and cancer prognosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Nomogram; Hepatocellular carcinoma; Proportional hazards model; Oncology; Internal medicine; Gene; DNA mismatch repair; Biology; DNA repair; Medicine; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001002403,0.0006981123,0.0005933605,0.001711185,0.0002239764,0.000780034,0.0002890876,0.0003491942,0.001849135],"category_scores_gemma":[0.001928201,0.0001175274,0.0007676314,0.001475636,0.0002049813,0.0003000672,0.0004728159,0.0004181277,0.0003680961],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00041473,"about_ca_system_score_gemma":0.000497327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001281179,"about_ca_topic_score_gemma":0.001042409,"domain_scores_codex":[0.9996446,0.000109535,0.00003140874,0.00009292056,0.00007813354,0.00004328335],"domain_scores_gemma":[0.9989083,0.0004128211,0.0003810227,0.00005948245,0.000140415,0.00009793109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008839668,0.00008439444,0.9344537,0.0003676802,0.0006024314,0.0002104842,0.0000524621,0.006238593,0.007648172,0.0004086702,0.001143396,0.04790609],"study_design_scores_gemma":[0.00008853443,0.0007222932,0.9048449,0.0002412418,0.001665168,0.001132328,0.0002345373,0.06454404,0.0141762,0.004179716,0.008089099,0.00008200397],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9647949,0.01362507,0.01249643,0.0008681546,0.00009667694,0.0000699432,0.006159571,0.0002183445,0.001670951],"genre_scores_gemma":[0.9926171,0.001024655,0.003405976,0.00007310475,0.00004172771,0.00003345327,0.002355785,0.00001279129,0.0004352952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001849135,"threshold_uncertainty_score":0.006186008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1509405767388284,"score_gpt":0.4111391770739326,"score_spread":0.2601986003351042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}