{"id":"W4388198297","doi":"10.3390/biom13111577","title":"Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease","year":2023,"lang":"en","type":"review","venue":"Biomolecules","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; McMaster Institute for Research on Aging, McMaster University; Canadian Institutes of Health Research; Consortium canadien en neurodégénérescence associée au vieillissement","keywords":"Brain-derived neurotrophic factor; Neurotrophic factors; Neuroscience; Disease; Expression (computer science); Psychology; Alzheimer's disease; Factor (programming language); Neurotrophin; Medicine; Internal medicine; Computer science; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007148816,0.000335225,0.0007515246,0.0002567217,0.00007849411,0.00001734534,0.0005534468,0.0001813899,0.00000541215],"category_scores_gemma":[0.0006239314,0.0002039758,0.0004533617,0.0005968053,0.0001466263,0.00004090926,0.0002002963,0.0001880594,0.00001548921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001857254,"about_ca_system_score_gemma":0.0001373835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007493682,"about_ca_topic_score_gemma":0.000002130868,"domain_scores_codex":[0.9976746,0.0006405694,0.0005317488,0.0005135458,0.0004288377,0.0002106477],"domain_scores_gemma":[0.9982882,0.0005734163,0.0005000337,0.0005442409,0.00001978287,0.00007436746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005899189,0.0002083018,3.7711e-7,0.008245984,0.000009968837,0.00006669576,0.00002747139,0.00001265245,0.9316114,0.002061608,0.00005304449,0.05764356],"study_design_scores_gemma":[0.0001779298,0.0001244789,0.00004115239,0.01980219,0.0001961891,0.000001085091,0.000001065651,0.00001841655,0.9775878,0.0004229589,0.001399942,0.0002267894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01382249,0.9801721,0.0001228262,0.0001404692,0.001823895,0.003408859,0.0004135299,0.00007943973,0.00001638608],"genre_scores_gemma":[0.04623202,0.9531798,0.00002326155,0.0001108742,0.00006661741,0.0002203956,0.00002255416,0.0001007457,0.00004369321],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.05741677,"threshold_uncertainty_score":0.831789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07258898547714564,"score_gpt":0.3300083734896538,"score_spread":0.2574193880125082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}