{"id":"W4388204031","doi":"10.3390/pharmaceutics15112533","title":"Investigation of Cannabinoid Acid/Cyclodextrin Inclusion Complex for Improving Physicochemical and Biological Performance","year":2023,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Research Foundation of Korea; University of Alberta","keywords":"Cannabinoid; Differential scanning calorimetry; Chemistry; Solubility; Cyclodextrin; Inclusion compound; Nuclear chemistry; Freeze-drying; Permeation; Chromatography; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003867858,0.0001171376,0.0002263283,0.0001154638,0.0001745204,0.000009558137,0.00008526863,0.00007989818,0.00001733967],"category_scores_gemma":[0.0001089677,0.00009705332,0.00006155474,0.0003449384,0.0002266842,0.00005021976,0.0004209481,0.0001855489,0.000003495549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005529675,"about_ca_system_score_gemma":0.0001073087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000153583,"about_ca_topic_score_gemma":7.982069e-7,"domain_scores_codex":[0.9989668,0.00002496281,0.0002306287,0.0002249936,0.0002534745,0.0002992074],"domain_scores_gemma":[0.9994142,0.0000231262,0.00006825924,0.0001300887,0.0001781442,0.0001861597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002256411,0.00002501231,0.01415935,0.0006945416,0.00001340683,0.000001940601,0.0003682712,0.000004805198,0.9508426,0.00005788021,0.00488929,0.02871722],"study_design_scores_gemma":[0.00188185,0.0003198429,0.04911316,0.00003756838,0.00004985871,0.00001377703,0.00008165625,0.08010533,0.8538015,0.0001944281,0.0142669,0.0001341687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994405,0.0002325366,0.00007802078,0.004491763,0.00005770643,0.0005579556,0.0000334488,0.00006807296,0.00007543578],"genre_scores_gemma":[0.9982499,0.0002565717,0.0003768339,0.0003739836,0.0001590456,0.00006850606,0.0001291826,0.00001741577,0.0003685062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09704118,"threshold_uncertainty_score":0.395772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1209515140763528,"score_gpt":0.3784496849663886,"score_spread":0.2574981708900358,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}