{"id":"W4388215021","doi":"10.1038/s41467-023-42732-2","title":"Production of leishmanin skin test antigen from Leishmania donovani for future reintroduction in the field","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill Genome Centre; McGill University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Government of Canada","keywords":"Cutaneous leishmaniasis; Vaccination; Antigen; Leishmaniasis; Immunology; Visceral leishmaniasis; Leishmania; Leishmania donovani; Skin test; Immune system; Medicine; Biology; Parasite hosting; Tuberculosis; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007303279,0.0004256175,0.0002391315,0.0002815486,0.0001717306,0.0004893697,0.0003238459,0.0004374751,0.002122188],"category_scores_gemma":[0.0004067218,0.0001582602,0.0002293361,0.0001971085,0.0002290966,0.0002557337,0.0003651405,0.0007468268,0.0007529448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001983033,"about_ca_system_score_gemma":0.0002556881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002662443,"about_ca_topic_score_gemma":0.000319406,"domain_scores_codex":[0.999749,0.0001216789,0.00001841173,0.00002907582,0.00004261983,0.00003922435],"domain_scores_gemma":[0.9997018,0.00008623918,0.00004108444,0.00005707422,0.00005529033,0.00005849164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000101104,0.0002107906,0.0005651261,0.00006770133,0.000005436254,0.00009386938,0.00002737926,0.0001245907,0.9951102,0.0001483523,0.0001933906,0.003352082],"study_design_scores_gemma":[0.0001545701,0.003756052,0.004761274,0.0000557459,0.00004047274,0.0006405769,0.0001228464,0.000820344,0.9675152,0.0003024167,0.02182014,0.00001036964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9599658,0.001869313,0.03066625,0.00090159,0.0002753183,0.001089615,0.001022849,0.0001755241,0.004033729],"genre_scores_gemma":[0.9585583,0.001160757,0.03185148,0.0003412538,0.00005033003,0.0003940237,0.003359027,0.00006453203,0.004220382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002122188,"threshold_uncertainty_score":0.00709945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03390512607279321,"score_gpt":0.3590712899756075,"score_spread":0.3251661639028143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}