{"id":"W4388217169","doi":"10.1136/bmjgh-2023-013480","title":"Expediting approval for medical countermeasures to address high burden disease: an ethical justification to move beyond emergency use authorisation","year":2023,"lang":"en","type":"review","venue":"BMJ Global Health","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Public Health Ontario; University of Toronto","funders":"Bill and Melinda Gates Foundation","keywords":"Panacea (medicine); Business; Expediting; Risk analysis (engineering); Equity (law); Medicine; Public relations; Political science; Economics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.136182,0.0006605035,0.001196277,0.0007920658,0.007614523,0.01646503,0.003260554,0.05158772,0.005552231],"category_scores_gemma":[0.2401143,0.0008394027,0.001870533,0.000602217,0.06146725,0.01696704,0.01151195,0.04441937,0.002652672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005708443,"about_ca_system_score_gemma":0.0221963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002361027,"about_ca_topic_score_gemma":0.003313807,"domain_scores_codex":[0.8201832,0.1326507,0.009464715,0.007888338,0.021629,0.00818405],"domain_scores_gemma":[0.6639936,0.259066,0.01879847,0.02500565,0.0184728,0.01466354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001245018,0.0001139234,0.001313518,0.0002987061,0.00003555509,0.001337435,0.01284027,0.0006197223,0.0009357943,0.8735595,0.08309719,0.02572379],"study_design_scores_gemma":[0.0001263653,0.0002196739,0.001041196,0.001669553,0.00004314148,0.002176325,0.005460737,0.00143976,0.001037226,0.5488197,0.4377661,0.000200188],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.005379704,0.00306387,0.01432471,0.9502107,0.00366452,0.00009472265,0.00002010394,0.00004829644,0.02319342],"genre_scores_gemma":[0.2816707,0.003098171,0.01915199,0.6725977,0.00677405,0.0003911697,0.0000327755,0.0001393403,0.01614412],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.136182,"threshold_uncertainty_score":0.7202076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2248691142922892,"score_gpt":0.5670509195908477,"score_spread":0.3421818052985585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}